PMC:4951402 / 6253-6852 JSONTXT

{"project":"2_test","denotations":[{"id":"27445649-17701901-44837776","span":{"begin":330,"end":332},"obj":"17701901"},{"id":"27445649-25653097-44837777","span":{"begin":366,"end":368},"obj":"25653097"},{"id":"27445649-22820512-44837778","span":{"begin":396,"end":398},"obj":"22820512"}],"text":"Genotype imputation\nAll missing genotypes were imputed in order to examine any potential effect of the unmeasured variants. We used 1,000 Genomes ASN Phase I integrated variant set release (v3) in National Center for Biotechnology Information (NCBI) build 37 (hg19) as a reference panel, along with PLINK software (version 1.07) [20] for strand alignment, SHAPEIT2 [21] for phasing, and IMPUTE2 [22] for the imputation procedure. Only variants with Info Score ≥0.9 were included in the final count, resulting in a total of 4,414,664 SNPs, which were either genotyped or imputed with high confidence."}