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{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/4928686","sourcedb":"PMC","sourceid":"4928686","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4928686","text":"Probably the most effective way to answer the question of whether CMV reactivation is pathogenic or merely a bystander in human disease will be properly controlled randomized trials with antiviral therapy [57]. In the case of immune-suppressed transplant patients, CMV was perceived as a definite pathogen, and this led to widespread antiviral use when such agents became available. It was not until decades later that properly controlled trials in immune-suppressed patients proved a benefit [58]. Fortunately, there has been a more circumspect and deliberate approach to antiviral treatment in critically ill patients with CMV reactivation.","tracks":[{"project":"2_test","denotations":[{"id":"25788396-17922387-121220515","span":{"begin":206,"end":208},"obj":"17922387"},{"id":"25788396-17922387-121220515","span":{"begin":206,"end":208},"obj":"17922387"},{"id":"25788396-16365468-121220516","span":{"begin":494,"end":496},"obj":"16365468"},{"id":"25788396-16365468-121220516","span":{"begin":494,"end":496},"obj":"16365468"},{"id":"25788396-17922387-68933196","span":{"begin":206,"end":208},"obj":"17922387"},{"id":"25788396-17922387-68933196","span":{"begin":206,"end":208},"obj":"17922387"},{"id":"25788396-16365468-68933197","span":{"begin":494,"end":496},"obj":"16365468"},{"id":"25788396-16365468-68933197","span":{"begin":494,"end":496},"obj":"16365468"}],"attributes":[{"subj":"25788396-17922387-121220515","pred":"source","obj":"2_test"},{"subj":"25788396-17922387-121220515","pred":"source","obj":"2_test"},{"subj":"25788396-16365468-121220516","pred":"source","obj":"2_test"},{"subj":"25788396-16365468-121220516","pred":"source","obj":"2_test"},{"subj":"25788396-17922387-68933196","pred":"source","obj":"2_test"},{"subj":"25788396-17922387-68933196","pred":"source","obj":"2_test"},{"subj":"25788396-16365468-68933197","pred":"source","obj":"2_test"},{"subj":"25788396-16365468-68933197","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#ecbf93","default":true}]}]}}