PMC:4928686 / 11383-11894 JSONTXT

{"project":"2_test","denotations":[{"id":"25788396-19531944-121220489","span":{"begin":168,"end":170},"obj":"19531944"},{"id":"25788396-19531944-121220489","span":{"begin":168,"end":170},"obj":"19531944"},{"id":"25788396-15793363-121220490","span":{"begin":353,"end":355},"obj":"15793363"},{"id":"25788396-15793363-121220490","span":{"begin":353,"end":355},"obj":"15793363"},{"id":"25788396-19176439-121220491","span":{"begin":507,"end":509},"obj":"19176439"},{"id":"25788396-19176439-121220491","span":{"begin":507,"end":509},"obj":"19176439"},{"id":"25788396-19531944-68933171","span":{"begin":168,"end":170},"obj":"19531944"},{"id":"25788396-19531944-68933171","span":{"begin":168,"end":170},"obj":"19531944"},{"id":"25788396-15793363-68933172","span":{"begin":353,"end":355},"obj":"15793363"},{"id":"25788396-15793363-68933172","span":{"begin":353,"end":355},"obj":"15793363"},{"id":"25788396-19176439-68933173","span":{"begin":507,"end":509},"obj":"19176439"},{"id":"25788396-19176439-68933173","span":{"begin":507,"end":509},"obj":"19176439"}],"text":"It is clear that patients that suffer CMV reactivation during their critical illness have an associated mortality of roughly double that of those without reactivation [49]. It is interesting that this mortality rate is similar to that seen in HIV patients with DNAemia (2-4X more likely to die)—independent of HIV load and CD4 counts and despite HAART [50]. Recent clinical data have suggested that it is not merely CMV, but the magnitude of the immune response to it that influences CMV-related mortality [42]."}