PMC:4845325 / 42398-43004 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/4845325","sourcedb":"PMC","sourceid":"4845325","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4845325","text":"To identify proteins with significant changes in plasma levels (based on Z-score values) we calculated permutation-corrected p-values (pcorr) for Control vs. AD for every protein (unpaired two-tailed t-test, 10,000 class label permutations) using the mattest Matlab function. To compute false-discovery rates, we adopted a direct approach to estimate q-values [64] using the mafdr Matlab function. Proteins with a significant difference between AD and Control samples and a q \u003c 0.05 were considered having different plasma levels (a total of 50 proteins). An identical approach was used for the svPPA data.","tracks":[]}