PMC:4718081 / 1867-2692
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4718081","sourcedb":"PMC","sourceid":"4718081","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4718081","text":"Neuropsychological tests such as Mini Mental State Examination (MMSE) and Clinical Dementia Rating (CDR) are widely used in the clinical evaluation of patients with suspected dementia (Powell et al., 2006). However, neuropsychological tests alone are inadequate to diagnose AD at the early stages (Zamrini et al., 2004). The biomarker-based assessment of AD has been proposed to enhance the clinical detection of AD in early prodromal stages of the disease (Dubois et al., 2007). The use of biomarkers in clinical diagnostics may help us to determine whether some mild cognitive impairment (MCI) symptoms are due to AD (Ewers et al., 2012).† Several researches have suggested that cerebrospinal fluid (CSF) based biomarkers are high precision risk factors in the disease process (Blennow and Hampel, 2003; Brys et al., 2009).","tracks":[{"project":"TEST0","denotations":[{"id":"26834548-200-208-278826","span":{"begin":200,"end":204},"obj":"[\"16769868\"]"},{"id":"26834548-107-115-278827","span":{"begin":314,"end":318},"obj":"[\"15172748\"]"},{"id":"26834548-152-160-278828","span":{"begin":473,"end":477},"obj":"[\"17616482\"]"},{"id":"26834548-154-162-278829","span":{"begin":634,"end":638},"obj":"[\"21159408\"]"},{"id":"26834548-160-168-278830","span":{"begin":800,"end":804},"obj":"[\"14505582\"]"},{"id":"26834548-179-187-278831","span":{"begin":819,"end":823},"obj":"[\"19221425\"]"}],"attributes":[{"subj":"26834548-200-208-278826","pred":"source","obj":"TEST0"},{"subj":"26834548-107-115-278827","pred":"source","obj":"TEST0"},{"subj":"26834548-152-160-278828","pred":"source","obj":"TEST0"},{"subj":"26834548-154-162-278829","pred":"source","obj":"TEST0"},{"subj":"26834548-160-168-278830","pred":"source","obj":"TEST0"},{"subj":"26834548-179-187-278831","pred":"source","obj":"TEST0"}]},{"project":"0_colil","denotations":[{"id":"26834548-16769868-278826","span":{"begin":200,"end":204},"obj":"16769868"},{"id":"26834548-15172748-278827","span":{"begin":314,"end":318},"obj":"15172748"},{"id":"26834548-17616482-278828","span":{"begin":473,"end":477},"obj":"17616482"},{"id":"26834548-21159408-278829","span":{"begin":634,"end":638},"obj":"21159408"},{"id":"26834548-14505582-278830","span":{"begin":800,"end":804},"obj":"14505582"},{"id":"26834548-19221425-278831","span":{"begin":819,"end":823},"obj":"19221425"}],"attributes":[{"subj":"26834548-16769868-278826","pred":"source","obj":"0_colil"},{"subj":"26834548-15172748-278827","pred":"source","obj":"0_colil"},{"subj":"26834548-17616482-278828","pred":"source","obj":"0_colil"},{"subj":"26834548-21159408-278829","pred":"source","obj":"0_colil"},{"subj":"26834548-14505582-278830","pred":"source","obj":"0_colil"},{"subj":"26834548-19221425-278831","pred":"source","obj":"0_colil"}]},{"project":"2_test","denotations":[{"id":"26834548-16769868-38218416","span":{"begin":200,"end":204},"obj":"16769868"},{"id":"26834548-15172748-38218417","span":{"begin":314,"end":318},"obj":"15172748"},{"id":"26834548-17616482-38218418","span":{"begin":473,"end":477},"obj":"17616482"},{"id":"26834548-21159408-38218419","span":{"begin":634,"end":638},"obj":"21159408"},{"id":"26834548-14505582-38218420","span":{"begin":800,"end":804},"obj":"14505582"},{"id":"26834548-19221425-38218421","span":{"begin":819,"end":823},"obj":"19221425"}],"attributes":[{"subj":"26834548-16769868-38218416","pred":"source","obj":"2_test"},{"subj":"26834548-15172748-38218417","pred":"source","obj":"2_test"},{"subj":"26834548-17616482-38218418","pred":"source","obj":"2_test"},{"subj":"26834548-21159408-38218419","pred":"source","obj":"2_test"},{"subj":"26834548-14505582-38218420","pred":"source","obj":"2_test"},{"subj":"26834548-19221425-38218421","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"TEST0","color":"#ec93de","default":true},{"id":"0_colil","color":"#93ece0"},{"id":"2_test","color":"#ecc593"}]}]}}