PMC:4718081 / 13957-15219 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4718081","sourcedb":"PMC","sourceid":"4718081","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4718081","text":"Evaluation of mini network balance\nMini network balance map (see Figure 6) is used to describe mini network imbalance visually. The closer to equilateral triangle the shape is, the less serious the mini network imbalance is. The results (Figure 6B) show that mini network imbalance deteriorates rapidly from 12 to 24 and 36 to 48 months while there is a plateau between the above two periods in both AD and MCI group, which coincide with the changes of MMSE.\nFigure 6 Mini network balance map of AD based on CSF biomarkers panel. (A) Mini network balance maps for the three groups at different time points. (B) Longitudinal mini network balance maps for the three groups. In normal state, the shape of mini network balance map is equilateral triangle. With the shape deformation, the mini network imbalance gets serious. The results of mini network disruption probability and MMSE are shown in the Figure 4. In AD group and MCI group, the mini network disruption probability increases rapidly between 12 and 24 months and there is a platform period from 24 to 36 months, then the disease progression turn into a rapid deterioration period until 48 months. In the normal control group, the mini network disruption probability keeps fluctuating during this study.","divisions":[{"label":"title","span":{"begin":0,"end":34}},{"label":"p","span":{"begin":35,"end":458}},{"label":"figure","span":{"begin":459,"end":821}},{"label":"label","span":{"begin":459,"end":467}},{"label":"caption","span":{"begin":469,"end":821}},{"label":"p","span":{"begin":469,"end":821}}],"tracks":[]}