PMC:4666274 / 12689-14296 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4666274","sourcedb":"PMC","sourceid":"4666274","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4666274","text":"Clinical assessment of ocular movements\nThe overall mean ROEM was reduced by 73 % in the patient group compared with controls (patients 13.3°, controls 49.3°, p \u003c 0.001; Table 3), with a consistent reduction in individual EOM ROEMs (Fig. 1A). There was no overlap between patient and control range of movement values for any muscle. There was no significant quantitative difference in ROEM detected between the right and left orbit in patients or controls, or between the CPEO and KSS subgroups, when muscles were compared both individually and collectively.\nTable 3 Mean range of eye movement, extra-ocular muscle cross-sectional area and T2 relaxation time in healthy control and patient groups\nControl Patient Difference\nMean s.d. n Max Min Mean s.d. n Max Min Mean (95 % CI) p-value\nROEM (degrees) 49.3 3.0 8 53.2 44.1 13.3 8.2 8 25.8 3.1 −36.0 (−42.6 to −29.3) \u003c0.001\nArea (mm2) 33.6 3.1 9 37.6 28.9 19.2 3.9 9 25.0 13.8 −14.4 (−17.9 to −10.8) \u003c0.001\nT2 (ms) 55.1 4.4 9 46.9 58.8 77.8 7.0 9 67.8 85.7 −22.7 (−28.4 to −16.9) \u003c0.001\nCI confidence interval, max maximum, min minimum, n number, ROEM range of eye movement, s.d. standard deviation\nFig. 1 Box plot of control (blue) and patient (green) values in each extra-ocular muscle: range of motion (A), cross-sectional area (B) and T2 relaxation time (C). The box represents 25th – 75th percentiles, the solid line in the box represents the median value, stems are to maximum and minimum values, o = minor outlier; + = major outlier. IO inferior oblique, IR inferior rectus, LR lateral rectus, MR medial rectus, SO superior oblique, SR superior rectus","divisions":[{"label":"title","span":{"begin":0,"end":39}},{"label":"table-wrap","span":{"begin":559,"end":1148}},{"label":"label","span":{"begin":559,"end":566}},{"label":"caption","span":{"begin":567,"end":696}},{"label":"p","span":{"begin":567,"end":696}},{"label":"table","span":{"begin":697,"end":1035}},{"label":"tr","span":{"begin":697,"end":723}},{"label":"th","span":{"begin":697,"end":704}},{"label":"th","span":{"begin":705,"end":712}},{"label":"th","span":{"begin":713,"end":723}},{"label":"tr","span":{"begin":724,"end":786}},{"label":"th","span":{"begin":724,"end":728}},{"label":"th","span":{"begin":729,"end":733}},{"label":"th","span":{"begin":734,"end":735}},{"label":"th","span":{"begin":736,"end":739}},{"label":"th","span":{"begin":740,"end":743}},{"label":"th","span":{"begin":744,"end":748}},{"label":"th","span":{"begin":749,"end":753}},{"label":"th","span":{"begin":754,"end":755}},{"label":"th","span":{"begin":756,"end":759}},{"label":"th","span":{"begin":760,"end":763}},{"label":"th","span":{"begin":764,"end":778}},{"label":"th","span":{"begin":779,"end":786}},{"label":"tr","span":{"begin":787,"end":872}},{"label":"td","span":{"begin":787,"end":801}},{"label":"td","span":{"begin":802,"end":806}},{"label":"td","span":{"begin":807,"end":810}},{"label":"td","span":{"begin":811,"end":812}},{"label":"td","span":{"begin":813,"end":817}},{"label":"td","span":{"begin":818,"end":822}},{"label":"td","span":{"begin":823,"end":827}},{"label":"td","span":{"begin":828,"end":831}},{"label":"td","span":{"begin":832,"end":833}},{"label":"td","span":{"begin":834,"end":838}},{"label":"td","span":{"begin":839,"end":842}},{"label":"td","span":{"begin":843,"end":865}},{"label":"td","span":{"begin":866,"end":872}},{"label":"tr","span":{"begin":873,"end":955}},{"label":"td","span":{"begin":873,"end":883}},{"label":"td","span":{"begin":884,"end":888}},{"label":"td","span":{"begin":889,"end":892}},{"label":"td","span":{"begin":893,"end":894}},{"label":"td","span":{"begin":895,"end":899}},{"label":"td","span":{"begin":900,"end":904}},{"label":"td","span":{"begin":905,"end":909}},{"label":"td","span":{"begin":910,"end":913}},{"label":"td","span":{"begin":914,"end":915}},{"label":"td","span":{"begin":916,"end":920}},{"label":"td","span":{"begin":921,"end":925}},{"label":"td","span":{"begin":926,"end":948}},{"label":"td","span":{"begin":949,"end":955}},{"label":"tr","span":{"begin":956,"end":1035}},{"label":"td","span":{"begin":956,"end":963}},{"label":"td","span":{"begin":964,"end":968}},{"label":"td","span":{"begin":969,"end":972}},{"label":"td","span":{"begin":973,"end":974}},{"label":"td","span":{"begin":975,"end":979}},{"label":"td","span":{"begin":980,"end":984}},{"label":"td","span":{"begin":985,"end":989}},{"label":"td","span":{"begin":990,"end":993}},{"label":"td","span":{"begin":994,"end":995}},{"label":"td","span":{"begin":996,"end":1000}},{"label":"td","span":{"begin":1001,"end":1005}},{"label":"td","span":{"begin":1006,"end":1028}},{"label":"td","span":{"begin":1029,"end":1035}},{"label":"table-wrap-foot","span":{"begin":1036,"end":1148}},{"label":"p","span":{"begin":1036,"end":1148}},{"label":"label","span":{"begin":1149,"end":1155}}],"tracks":[]}