PMC:4631427 / 19660-20657 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4631427","sourcedb":"PMC","sourceid":"4631427","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4631427","text":"When reviewing anticipatory guidance for possible reactions, education regarding potential for future severe reactions despite severity of previous reactions is also extremely important. A common misconception is that severity of past reactions will predict future outcomes.64 For example, if a child developed hives upon his first reaction to peanut, the parents may assume each additional exposure will only elicit hives, and the condition is (inappropriately) thought of as a “mild allergy”. The provider should discuss that regardless of previous symptoms, any future accidental ingestion may result in a severe, life-threatening reactions. One study from 2005 used double-blind, placebo-controlled food challenges in patients allergic to peanuts and found poor correlation between severity of reported reactions and reactions elicited in the challenge. Furthermore, only the most recent community reaction predicted severity of challenge-based reactions, but even this association was weak.64","tracks":[{"project":"TEST0","denotations":[{"id":"26604803-237-243-1382683","span":{"begin":274,"end":276},"obj":"[\"16164452\"]"},{"id":"26604803-137-143-1382684","span":{"begin":995,"end":997},"obj":"[\"16164452\"]"}],"attributes":[{"subj":"26604803-237-243-1382683","pred":"source","obj":"TEST0"},{"subj":"26604803-137-143-1382684","pred":"source","obj":"TEST0"}]},{"project":"2_test","denotations":[{"id":"26604803-16164452-55579378","span":{"begin":274,"end":276},"obj":"16164452"},{"id":"26604803-16164452-55579379","span":{"begin":995,"end":997},"obj":"16164452"}],"attributes":[{"subj":"26604803-16164452-55579378","pred":"source","obj":"2_test"},{"subj":"26604803-16164452-55579379","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"TEST0","color":"#96ec93","default":true},{"id":"2_test","color":"#ec93b0"}]}]}}