PMC:4630240 / 17572-18932 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4630240","sourcedb":"PMC","sourceid":"4630240","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4630240","text":"In the rm-ANOVA model with N1–P1 peak-peak amplitude as dependent variable, multivariate test was significant for the “group” × “blocks” interaction effect (Wilks’ Lambda = 0.745, F5,71 = 4.862, p = 0.0007) (Table 3). After checking that the sphericity assumption was not violated (Mauchley Test: p = 0.104), univariate rm-ANOVAs for N1–P1 peak-peak amplitude confirmed the significant interaction factor effect (F5,375 = 5.261, p = 0.0001, partial η2 = 0.066, op = 0.988) observed (see above) at the multivariate test. Post-hoc analysis showed that VEP amplitudes differed between groups only in the last block (5.97 μV in HV vs. 7.42 μV in MAtot, p = 0.038, raw data are shown in Fig. 2). In HV, N1–P1 amplitude was significantly lower in the 6th compared to the 1st block (p = 0.0008). This was not so in MAtot, where this comparison did not reach the significance level (p = 0.994).\nFig. 2 Raw amplitudes (mean ± SEM) of N1-P1 (upper graphs) and P1-N2 (lower graphs) VEP components in 6 sequential blocks of 100 recordings. On the left healthy volunteers [HV, n = 30] are compared to the total group of migraine with aura patients [MAtot, n = 47]; on the right they are compared to the 2 subgroups of patients with pure visual aura [MA, n = 27] and patients with complex aura [MA+, n = 20]. ≠ p \u003c 0.05 MAtot vs HV; *p \u003c 0.05 MA+ vs MA; § p \u003c 0.05 MA+ vs HV","divisions":[{"label":"label","span":{"begin":887,"end":893}}],"tracks":[]}