PMC:4627622 / 25431-26008 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4627622","sourcedb":"PMC","sourceid":"4627622","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4627622","text":"Conclusion\nIn conclusion, we observed that [51Cr]-EDTA does not pass to the CNS in a major way. However, [51Cr]-EDTA readily passed the TG by \u003e30 times compared to the CNS. Application of CFA or IS (studied at 2, 24 or 48 h after the application) did not show altered transfer constant to [51Cr]-EDTA. Thus, with these experiments we suggest; (i) dural triggered TG inflammation, with IS or CFA does not change BBB passage, and (ii) the TG is readily exposed to circulating molecules and could provide a site where anti-migraine drugs could interact with the trigeminal system.","divisions":[{"label":"title","span":{"begin":0,"end":10}}],"tracks":[]}