PMC:4627622 / 17993-19426 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4627622","sourcedb":"PMC","sourceid":"4627622","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4627622","text":"We further characterized the changes in permeability following the addition of CFA and IS onto the dura. There were no significant increases in the permeability of the cortex, cerebellum or PAG following either of the inflammation triggers (Fig. 3) compared to vehicle, suggesting that permeability does not change in the inflammatory models. A small permeability increase in the spinal TNC was observed after 24 h of CFA, although the change is nearly negligible as it after CFA still is \u003e10 times less permeable than the TG (Fig. 4). We observed a small decrease in the left TG with the same tendency in the right TG, which could be due to the increased ganglion activation. We did not observe any significant changes in any of the structures examined after either 2 or 24 h after the addition of IS.\nFig. 3 PS in the cortex cerebellum and PAG after treatment with CFA or IS. The figure shows PS for 51Cr-EDTA in the cortex (a), cerebellum (b) and periaquaductal grey (c). PS for treatment following application of CFA or IS to the dura was compared to PS following application of vehicle to the dura. *p ≤0.05\nFig. 4 PS in the TG and spinal trigeminal nucleus after treatment with CFA or IS. The figure shows PS for 51Cr-EDTA in the left TNC (a), right TNC (b), left TG (c), and right TG (d). PS for treatment following application of CFA or IS to the dura was compared to PS following application of vehicle to the dura. *p ≤0.05","divisions":[{"label":"figure","span":{"begin":803,"end":1112}},{"label":"label","span":{"begin":803,"end":809}},{"label":"caption","span":{"begin":810,"end":1112}},{"label":"p","span":{"begin":810,"end":1112}},{"label":"label","span":{"begin":1113,"end":1119}}],"tracks":[]}