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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4572492","sourcedb":"PMC","sourceid":"4572492","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4572492","text":"Large values of WF correspond to small values of pL and/or pS and provide evidence against the null H0joint. If pL and pS are independent under H0joint, WF is distributed as a χ42 random variable. Although Fisher’s method here is used to combine evidence from two tests applied to the same sample, the assumption of independence between pL and pS under H0joint holds theoretically for a normally distributed trait (Appendix A, Lemma 1), as well as empirically for approximately normally distributed traits in finite samples (Figures S1 and S2, Tables S1 and S2).","tracks":[]}