PMC:4536239 / 12009-13818 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4536239","sourcedb":"PMC","sourceid":"4536239","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4536239","text":"Of 143 migraine subjects, 13 (9.1 %) were classified as having RLS. Of 1,130 non-migraine headache subjects and 1,422 non-headache control subjects, 78 (6.9 %) and 51 (3.6 %) subjects were classified as having RLS, respectively. A significantly greater prevalence of RLS was observed in both subjects with migraine (OR = 2.6, 95 % CI = 1.4–5.0, p = 0.003) and non-migraine headaches (OR = 2.1, 95 % CI = 1.4–2.9, p \u003c 0.001) relative to non-headache control subjects. This pattern was consistent even after adjusting for sociodemographic variables (age, gender, educational level, and size of residential area) and sleep quality (PSQI score \u003e5) (Table 2). There was no significant difference (9.1 % vs. 6.9 %, p = 0.339) in the RLS prevalence between migraineurs and non-migraine headache subjects.\nTable 2 Prevalence and odds ratios of restless legs syndrome according to headache diagnosis\nAge group, No of participants/ No. of RLS Non-headache control, N = 1,422 Non-migraine headache, N = 1,130 Migraine, N = 143\nNo. of RLS (%) OR No. of RLS (%) OR (95 % CI) P-value No. of RLS (%) OR (95 % CI) P-value\nAged 19–29, 542/12 4 (1.4) Reference 5 (2.2) 1.3 (0.4–5.0) 0.701 3 (12.0) 6.6 (1.2–36.8) 0.029\nAged 30–39, 604/34 6 (2.0) Reference 25 (9.3) 4.6 (1.8–12.0) 0.002 3 (7.1) 2.9 (0.6–13.4) 0.176\nAged 40–49, 611/20 3 (1.0) Reference 13 (4.7) 3.7 (1.0–13.5) 0.046 4 (10.3) 6.7 (1.5–33.5) 0.016\nAged 50–59, 529/35 17 (5.6) Reference 16 (7.8) 1.3 (0.6–2.7) 0.553 2 (9.1) 1.1 (0.2–5.6) 0.902\nAged 60–69, 409/41 21 (8.6) Reference 19 (12.8) 1.3 (0.6–2.5) 0.506 1 (6.7) 0.4 (0.1–4.0) 0.459\nTotal, 2695/142 51 (3.6) Reference 78 (6.9) 1.8 (1.3–2.7)a 0.002a 13 (9.1) 2.2 (1.1–4.3)a 0.018a\nCI confidence interval, OR odds ratio, RLS restless legs syndrome\naAdjusted after sociodemographic variables and sleep quality\n","divisions":[{"label":"label","span":{"begin":798,"end":805}},{"label":"caption","span":{"begin":806,"end":890}},{"label":"p","span":{"begin":806,"end":890}},{"label":"table","span":{"begin":891,"end":1681}},{"label":"tr","span":{"begin":891,"end":1015}},{"label":"th","span":{"begin":891,"end":932}},{"label":"th","span":{"begin":933,"end":964}},{"label":"th","span":{"begin":965,"end":997}},{"label":"th","span":{"begin":998,"end":1015}},{"label":"tr","span":{"begin":1016,"end":1105}},{"label":"th","span":{"begin":1016,"end":1030}},{"label":"th","span":{"begin":1031,"end":1033}},{"label":"th","span":{"begin":1034,"end":1048}},{"label":"th","span":{"begin":1049,"end":1061}},{"label":"th","span":{"begin":1062,"end":1069}},{"label":"th","span":{"begin":1070,"end":1084}},{"label":"th","span":{"begin":1085,"end":1097}},{"label":"th","span":{"begin":1098,"end":1105}},{"label":"tr","span":{"begin":1106,"end":1200}},{"label":"td","span":{"begin":1106,"end":1124}},{"label":"td","span":{"begin":1125,"end":1132}},{"label":"td","span":{"begin":1133,"end":1142}},{"label":"td","span":{"begin":1143,"end":1150}},{"label":"td","span":{"begin":1151,"end":1164}},{"label":"td","span":{"begin":1165,"end":1170}},{"label":"td","span":{"begin":1171,"end":1179}},{"label":"td","span":{"begin":1180,"end":1194}},{"label":"td","span":{"begin":1195,"end":1200}},{"label":"tr","span":{"begin":1201,"end":1296}},{"label":"td","span":{"begin":1201,"end":1219}},{"label":"td","span":{"begin":1220,"end":1227}},{"label":"td","span":{"begin":1228,"end":1237}},{"label":"td","span":{"begin":1238,"end":1246}},{"label":"td","span":{"begin":1247,"end":1261}},{"label":"td","span":{"begin":1262,"end":1267}},{"label":"td","span":{"begin":1268,"end":1275}},{"label":"td","span":{"begin":1276,"end":1290}},{"label":"td","span":{"begin":1291,"end":1296}},{"label":"tr","span":{"begin":1297,"end":1393}},{"label":"td","span":{"begin":1297,"end":1315}},{"label":"td","span":{"begin":1316,"end":1323}},{"label":"td","span":{"begin":1324,"end":1333}},{"label":"td","span":{"begin":1334,"end":1342}},{"label":"td","span":{"begin":1343,"end":1357}},{"label":"td","span":{"begin":1358,"end":1363}},{"label":"td","span":{"begin":1364,"end":1372}},{"label":"td","span":{"begin":1373,"end":1387}},{"label":"td","span":{"begin":1388,"end":1393}},{"label":"tr","span":{"begin":1394,"end":1488}},{"label":"td","span":{"begin":1394,"end":1412}},{"label":"td","span":{"begin":1413,"end":1421}},{"label":"td","span":{"begin":1422,"end":1431}},{"label":"td","span":{"begin":1432,"end":1440}},{"label":"td","span":{"begin":1441,"end":1454}},{"label":"td","span":{"begin":1455,"end":1460}},{"label":"td","span":{"begin":1461,"end":1468}},{"label":"td","span":{"begin":1469,"end":1482}},{"label":"td","span":{"begin":1483,"end":1488}},{"label":"tr","span":{"begin":1489,"end":1584}},{"label":"td","span":{"begin":1489,"end":1507}},{"label":"td","span":{"begin":1508,"end":1516}},{"label":"td","span":{"begin":1517,"end":1526}},{"label":"td","span":{"begin":1527,"end":1536}},{"label":"td","span":{"begin":1537,"end":1550}},{"label":"td","span":{"begin":1551,"end":1556}},{"label":"td","span":{"begin":1557,"end":1564}},{"label":"td","span":{"begin":1565,"end":1578}},{"label":"td","span":{"begin":1579,"end":1584}},{"label":"tr","span":{"begin":1585,"end":1681}},{"label":"td","span":{"begin":1585,"end":1600}},{"label":"td","span":{"begin":1601,"end":1609}},{"label":"td","span":{"begin":1610,"end":1619}},{"label":"td","span":{"begin":1620,"end":1628}},{"label":"td","span":{"begin":1629,"end":1643}},{"label":"td","span":{"begin":1644,"end":1650}},{"label":"td","span":{"begin":1651,"end":1659}},{"label":"td","span":{"begin":1660,"end":1674}},{"label":"td","span":{"begin":1675,"end":1681}},{"label":"p","span":{"begin":1682,"end":1748}}],"tracks":[]}