PMC:4504005 / 41350-41831 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4504005","sourcedb":"PMC","sourceid":"4504005","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4504005","text":"(A) Superposition of the CGRPmut- and AM-bound ECD heterodimers aligned based on the CLR positions. The receptors and peptides are in cartoon representation with selected residues as sticks in the left image. In the right image, the receptors are Cα traces and the peptide cartoons were omitted for clarity. Arrows indicate directions of movement of CLR α1 and loop 2 and RAMP α2 and α3 from the CGRPmut/RAMP1-bound state to the AM/RAMP2-bound state. Red dashes are hydrogen bonds.","tracks":[]}