PMC:4504005 / 35461-37101 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4504005","sourcedb":"PMC","sourceid":"4504005","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4504005","text":"Accession Numbers\nThe accession numbers for the coordinates and structure factors reported in this paper for the AM:CLR:RAMP2 and CGRPmut:CLR:RAMP1 complexes, respectively are PDB: 4RWF, 4RWG.\n\nSupplemental Information\nDocument S1. Supplemental Experimental Procedures, Figures S1 and S2, and Tables S1–S4\nDocument S2. Article plus Supplemental Information\n\nAcknowledgments\nThis research was supported by NIH grant R01GM104251 (A.A.P.), Wellcome Trust grant 091496 (D.R.P.), and grants from the Marsden Fund and Health Research Council of New Zealand (D.L.H.). Use of the Leica microscope for crystal imaging was supported by an Institutional Developmental Award from the National Institute of General Medical Sciences of the NIH under grant number P20GM103640. Use of the Advanced Photon Source, an Office of Science User Facility operated for the U.S. Department of Energy (DOE) Office of Science by Argonne National Laboratory, was supported by the U.S. DOE under Contract No. DE-AC02-06CH11357. Use of the LS-CAT Sector 21 was supported by the Michigan Economic Development Corporation and the Michigan Technology Tri-Corridor (Grant 085P1000817). We thank Zdzislaw Wawrzak and Spencer Anderson for assistance with remote data collection at APS sector 21 and Amanda Roehrkasse for pilot studies with the tethered RAMP1-(GSA)3-CLR construct. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).\nSupplemental Information includes Supplemental Experimental Procedures, two figures, and four tables and can be found with this article online at http://dx.doi.org/10.1016/j.molcel.2015.04.018.","divisions":[{"label":"sec","span":{"begin":0,"end":192}},{"label":"title","span":{"begin":0,"end":17}},{"label":"p","span":{"begin":18,"end":192}},{"label":"sec","span":{"begin":194,"end":356}},{"label":"title","span":{"begin":194,"end":218}},{"label":"p","span":{"begin":219,"end":356}},{"label":"caption","span":{"begin":219,"end":305}},{"label":"title","span":{"begin":219,"end":305}},{"label":"caption","span":{"begin":306,"end":356}},{"label":"title","span":{"begin":306,"end":356}},{"label":"ack","span":{"begin":358,"end":1344}},{"label":"title","span":{"begin":358,"end":373}},{"label":"p","span":{"begin":374,"end":1344}},{"label":"footnote","span":{"begin":1345,"end":1446}},{"label":"p","span":{"begin":1345,"end":1446}}],"tracks":[]}