PMC:4502373 / 43815-44844 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/4502373","sourcedb":"PMC","sourceid":"4502373","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4502373","text":"No candidate gene regions were found in common across the European and African cattle types. This may be due to the long-term differences in natural and production-oriented selective pressures in these diverse genetic archetypes (Edea et al. 2014; Gautier et al. 2009; Gautier and Naves 2011; Gibbs et al. 2009; Randhawa et al. 2014). Recent attempts to find the transferability of height-associated loci across human populations have shown comparable results (low consistency) for finding the same genetic variants when discoveries made in non-African ethnicities were compared in populations of African ancestry (Kang et al. 2010; Shriner et al. 2009). Our results indicate that there may be a persistent trend of dissimilarities for African genealogies across species, and some environmental factors would have shaped a comparatively different genetic architecture. We suggest that investigation of several other African breeds with sufficient sample sizes can further elaborate the nature of different candidate gene regions.","tracks":[{"project":"2_test","denotations":[{"id":"25931611-19930592-43349864","span":{"begin":263,"end":267},"obj":"19930592"},{"id":"25931611-21689193-43349865","span":{"begin":287,"end":291},"obj":"21689193"},{"id":"25931611-19390050-43349866","span":{"begin":306,"end":310},"obj":"19390050"},{"id":"25931611-24636660-43349867","span":{"begin":328,"end":332},"obj":"24636660"},{"id":"25931611-20400458-43349868","span":{"begin":627,"end":631},"obj":"20400458"},{"id":"25931611-20027299-43349869","span":{"begin":648,"end":652},"obj":"20027299"}],"attributes":[{"subj":"25931611-19930592-43349864","pred":"source","obj":"2_test"},{"subj":"25931611-21689193-43349865","pred":"source","obj":"2_test"},{"subj":"25931611-19390050-43349866","pred":"source","obj":"2_test"},{"subj":"25931611-24636660-43349867","pred":"source","obj":"2_test"},{"subj":"25931611-20400458-43349868","pred":"source","obj":"2_test"},{"subj":"25931611-20027299-43349869","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#93ecec","default":true}]}]}}