PMC:4502373 / 39374-40501 JSONTXT

{"project":"2_test","denotations":[{"id":"25931611-19393047-43349810","span":{"begin":346,"end":350},"obj":"19393047"},{"id":"25931611-23859468-43349811","span":{"begin":365,"end":369},"obj":"23859468"},{"id":"25931611-19672461-43349812","span":{"begin":384,"end":388},"obj":"19672461"},{"id":"25931611-19390050-43349813","span":{"begin":403,"end":407},"obj":"19390050"},{"id":"25931611-24678841-43349814","span":{"begin":423,"end":427},"obj":"24678841"},{"id":"25931611-24442315-43349815","span":{"begin":444,"end":448},"obj":"24442315"},{"id":"25931611-23889699-43349816","span":{"begin":464,"end":468},"obj":"23889699"},{"id":"25931611-24592996-43349821","span":{"begin":571,"end":575},"obj":"24592996"},{"id":"25931611-18391951-43349822","span":{"begin":694,"end":698},"obj":"18391951"},{"id":"25931611-19343178-43349823","span":{"begin":715,"end":719},"obj":"19343178"},{"id":"25931611-20189936-43349824","span":{"begin":734,"end":738},"obj":"20189936"},{"id":"25931611-18391950-43349825","span":{"begin":754,"end":758},"obj":"18391950"},{"id":"25931611-20881960-43349826","span":{"begin":779,"end":783},"obj":"20881960"},{"id":"25931611-22607022-43349827","span":{"begin":825,"end":829},"obj":"22607022"},{"id":"25931611-21212230-43349828","span":{"begin":844,"end":848},"obj":"21212230"}],"text":"Validation of known stature-associated genomic regions in cattle\nThis study validated two important candidate gene regions (regions 6 and 10) linked to stature in European breeds of cattle. Region 6 harboring NCAPG and LCORL genes located on BTA-6 has frequently shown strong signatures of selection in multiple breeds of cattle (Barendse et al. 2009; Druet et al. 2013; Flori et al. 2009; Gibbs et al. 2009; Kemper et al. 2014; Mancini et al. 2014; Pintus et al. 2013; Porto-Neto et al. 2013; Rothammer et al. 2013; Stella et al. 2010; Qanbari et al. 2014; Perez et al. 2014). Region 10 harboring PLAG1 and CHCHD7 genes on BTA-14 has been associated with height in humans (Gudbjartsson et al. 2008; Soranzo et al. 2009; Okada et al. 2010; Lettre et al. 2008; Lango Allen et al. 2010) and stature in cattle (Nishimura et al. 2012; Pryce et al. 2011; Karim et al. 2011; Fortes et al. 2013; Bolormaa et al. 2014). This locus was also identified as a candidate region based on selective sweeps in several cattle breeds that have been under strong selection for body size (Druet et al. 2013; Ramey et al. 2013; Kemper et al. 2014)."}