PMC:4502372 / 23419-23965 JSONTXT

{"project":"2_test","denotations":[{"id":"25943524-12191482-43313285","span":{"begin":357,"end":361},"obj":"12191482"},{"id":"25943524-17325030-43313286","span":{"begin":503,"end":507},"obj":"17325030"},{"id":"25943524-12667463-43313287","span":{"begin":522,"end":526},"obj":"12667463"},{"id":"25943524-12191482-43313288","span":{"begin":540,"end":544},"obj":"12191482"}],"text":"The delay in colony formation in the sea3∆ mutant BIR assay strain suggested that sea3∆ mutants may have a delay in recovery post-DNA damage. Recovery is typically defined as resumption of mitosis after repair is completed and the checkpoint is turned off; recovery mutants demonstrate sustained activation of the DDR despite repair of the DSB (Vaze et al. 2002). A variety of proteins have been implicated in recovery and most are associated with the DNA damage checkpoint or repair (Guillemain et al. 2007; Leroy et al. 2003; Vaze et al. 2002)."}