PMC:4502370 / 6141-6560 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/4502370","sourcedb":"PMC","sourceid":"4502370","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4502370","text":"Despite these discouraging results, we continued the search for tgs1∆ suppressors along two lines, one U1-centric, and one unbiased. As we report here, both approaches bore fruit. In the first instance, we generated a series of viable truncation mutants of U1 subunit Snp1 and screened them for genetic interactions. We found two C-terminal truncations of Snp1 that restored the growth of tgs1∆ cell at low temperature.","tracks":[]}