PMC:4502367 / 14793-15721 JSONTXT

{"target":"http://pubannotation.org/docs/sourcedb/PMC/sourceid/4502367","sourcedb":"PMC","sourceid":"4502367","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4502367","text":"Secretome prediction\nPlant pathogens secrete proteins to interfere with host immune defenses. Genes encoding secreted proteins are therefore of particular interest due to their potential role in infection and host–pathogen interaction. We screened predicted proteins for the presence of signal peptides and categorized proteins as secreted under the following conditions: (i) if a signal peptide was predicted by both Neural-Network and HMM methods by the software SignalP 3.0 (Emanuelsson et al. 2007); (ii) if zero or one transmembrane domain was present in the protein (the domain having at least 30% overlap with the signal peptide) using the software TMHMM 2.0 (Krogh et al. 2001); and (iii) if the protein was predicted to be targeted to the secretory pathway by the software TargetP 1.1 (Emanuelsson et al. 2007). Secreted proteins with a size of 300 amino acids or less were considered as small secreted proteins (SSPs).","divisions":[{"label":"title","span":{"begin":0,"end":20}}],"tracks":[{"project":"2_test","denotations":[{"id":"25917918-17446895-43386555","span":{"begin":497,"end":501},"obj":"17446895"},{"id":"25917918-11152613-43386556","span":{"begin":680,"end":684},"obj":"11152613"},{"id":"25917918-17446895-43386557","span":{"begin":814,"end":818},"obj":"17446895"}],"attributes":[{"subj":"25917918-17446895-43386555","pred":"source","obj":"2_test"},{"subj":"25917918-11152613-43386556","pred":"source","obj":"2_test"},{"subj":"25917918-17446895-43386557","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#93ece0","default":true}]}]}}