PMC:4429232 / 12852-14630
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4429232","sourcedb":"PMC","sourceid":"4429232","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4429232","text":"Some evidences against the first two hypotheses were first presented by Ebner based on hodological considerations (Ebner, 1976). Indeed, reptilian dorsal cortex neurons have projections to subcortical targets that resemble those of neocortical DL neurons but lack the extensive network of intracortical connections, including homotopic contralateral projections, that are typical of UL neurons (Ebner, 1976; Desan, 1984; Hoogland and Vermeulen-Vanderzee, 1989). Thus, Ebner proposed that the UL neurons may represent an evolutionary novelty. In the early'90 Anton Reiner extended Ebner hypotheses by showing that UL specific interneurons are lacking from the reptilian dorsal cortex (Reiner, 1991, 1993). However, later studies showed that interneurons are generated in the sub-pallium (Cobos et al., 2001; Wichterle et al., 2001) and this makes the Reneir's observations only indirectly related to the DP progenitors developmental program. In 2009 we described a specific population of neurons of the layer II of the neocortex that according with Ebner and Reiner ideas was absent from the dorsal cortex of Lacerta Muralis, a lizard. However, virtually identical cell types were observed in the LP and VP derivatives of both lizard and mammals thus supporting the spatial to temporal patterning switch hypothesis (Luzzati et al., 2009). The interest about these cells comes from the fact that (1) they express Tbr1, suggesting a pallial origin, and (2) morphological and distributive features support that they represent a specific neuronal population that is shared by different pallial derivatives and tetrapod species. In the following sections we will describe and discuss in detail our observations in the context of more recent data that further support these hypotheses.","tracks":[{"project":"0_colil","denotations":[{"id":"26029038-2760266-565813","span":{"begin":455,"end":459},"obj":"2760266"},{"id":"26029038-1683805-565814","span":{"begin":692,"end":696},"obj":"1683805"},{"id":"26029038-8097979-565815","span":{"begin":698,"end":702},"obj":"8097979"},{"id":"26029038-11784017-565816","span":{"begin":801,"end":805},"obj":"11784017"},{"id":"26029038-11585802-565817","span":{"begin":825,"end":829},"obj":"11585802"},{"id":"26029038-18832334-565818","span":{"begin":1331,"end":1335},"obj":"18832334"}],"attributes":[{"subj":"26029038-2760266-565813","pred":"source","obj":"0_colil"},{"subj":"26029038-1683805-565814","pred":"source","obj":"0_colil"},{"subj":"26029038-8097979-565815","pred":"source","obj":"0_colil"},{"subj":"26029038-11784017-565816","pred":"source","obj":"0_colil"},{"subj":"26029038-11585802-565817","pred":"source","obj":"0_colil"},{"subj":"26029038-18832334-565818","pred":"source","obj":"0_colil"}]},{"project":"2_test","denotations":[{"id":"26029038-2760266-38462719","span":{"begin":455,"end":459},"obj":"2760266"},{"id":"26029038-1683805-38462720","span":{"begin":692,"end":696},"obj":"1683805"},{"id":"26029038-8097979-38462721","span":{"begin":698,"end":702},"obj":"8097979"},{"id":"26029038-11784017-38462722","span":{"begin":801,"end":805},"obj":"11784017"},{"id":"26029038-11585802-38462723","span":{"begin":825,"end":829},"obj":"11585802"},{"id":"26029038-18832334-38462724","span":{"begin":1331,"end":1335},"obj":"18832334"}],"attributes":[{"subj":"26029038-2760266-38462719","pred":"source","obj":"2_test"},{"subj":"26029038-1683805-38462720","pred":"source","obj":"2_test"},{"subj":"26029038-8097979-38462721","pred":"source","obj":"2_test"},{"subj":"26029038-11784017-38462722","pred":"source","obj":"2_test"},{"subj":"26029038-11585802-38462723","pred":"source","obj":"2_test"},{"subj":"26029038-18832334-38462724","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"0_colil","color":"#93b9ec","default":true},{"id":"2_test","color":"#d3ec93"}]}]}}