Id |
Subject |
Object |
Predicate |
Lexical cue |
T7178 |
0-3 |
DT |
denotes |
The |
T7179 |
24-33 |
NN |
denotes |
structure |
T7180 |
4-11 |
NN |
denotes |
protein |
T7181 |
12-15 |
CC |
denotes |
and |
T7182 |
16-23 |
JJ |
denotes |
genomic |
T7183 |
73-81 |
VBZ |
denotes |
suggests |
T7184 |
34-36 |
IN |
denotes |
of |
T7185 |
37-40 |
DT |
denotes |
the |
T7186 |
65-72 |
NNS |
denotes |
members |
T7187 |
41-48 |
JJ |
denotes |
present |
T7188 |
49-52 |
NN |
denotes |
day |
T7189 |
53-57 |
NN |
denotes |
TACC |
T7190 |
58-64 |
NN |
denotes |
family |
T7191 |
82-86 |
IN |
denotes |
that |
T7192 |
134-142 |
VBN |
denotes |
mediated |
T7193 |
87-90 |
DT |
denotes |
the |
T7194 |
91-99 |
NN |
denotes |
function |
T7195 |
100-102 |
IN |
denotes |
of |
T7196 |
103-106 |
DT |
denotes |
the |
T7197 |
122-129 |
NN |
denotes |
protein |
T7198 |
107-116 |
JJ |
denotes |
ancestral |
T7199 |
117-121 |
NN |
denotes |
TACC |
T7200 |
130-133 |
VBD |
denotes |
was |
T7201 |
143-149 |
RB |
denotes |
solely |
T7202 |
150-157 |
IN |
denotes |
through |
T7203 |
158-161 |
DT |
denotes |
the |
T7204 |
162-174 |
NNS |
denotes |
interactions |
T7205 |
175-177 |
IN |
denotes |
of |
T7206 |
178-181 |
DT |
denotes |
the |
T7207 |
197-203 |
NN |
denotes |
domain |
T7208 |
182-191 |
VBN |
denotes |
conserved |
T7209 |
192-196 |
NN |
denotes |
TACC |
T7210 |
203-204 |
. |
denotes |
. |
T7211 |
204-503 |
sentence |
denotes |
Using an in silico protein-protein interaction model based upon known mitotic spindle and centrosomal components, we have previously predicted a number of additional interactions that could be conserved between a functional TACC homologue in yeast, spc-72, and one or more human TACC proteins [21]. |
T7212 |
205-210 |
VBG |
denotes |
Using |
T7213 |
338-347 |
VBN |
denotes |
predicted |
T7214 |
211-213 |
DT |
denotes |
an |
T7215 |
252-257 |
NN |
denotes |
model |
T7216 |
214-216 |
FW |
denotes |
in |
T7217 |
217-223 |
FW |
denotes |
silico |
T7218 |
224-231 |
NN |
denotes |
protein |
T7219 |
232-239 |
NN |
denotes |
protein |
T7220 |
231-232 |
HYPH |
denotes |
- |
T7221 |
240-251 |
NN |
denotes |
interaction |
T7222 |
258-263 |
VBN |
denotes |
based |
T7223 |
264-268 |
IN |
denotes |
upon |
T7224 |
269-274 |
JJ |
denotes |
known |
T7225 |
307-317 |
NNS |
denotes |
components |
T7226 |
275-282 |
JJ |
denotes |
mitotic |
T7227 |
283-290 |
NN |
denotes |
spindle |
T7228 |
291-294 |
CC |
denotes |
and |
T7229 |
295-306 |
JJ |
denotes |
centrosomal |
T7230 |
317-319 |
, |
denotes |
, |
T7231 |
319-321 |
PRP |
denotes |
we |
T7232 |
322-326 |
VBP |
denotes |
have |
T7233 |
327-337 |
RB |
denotes |
previously |
T7234 |
348-349 |
DT |
denotes |
a |
T7235 |
350-356 |
NN |
denotes |
number |
T7236 |
357-359 |
IN |
denotes |
of |
T7237 |
360-370 |
JJ |
denotes |
additional |
T7238 |
371-383 |
NNS |
denotes |
interactions |
T7239 |
384-388 |
WDT |
denotes |
that |
T7240 |
398-407 |
VBN |
denotes |
conserved |
T7241 |
389-394 |
MD |
denotes |
could |
T7242 |
395-397 |
VB |
denotes |
be |
T7243 |
408-415 |
IN |
denotes |
between |
T7244 |
416-417 |
DT |
denotes |
a |
T7245 |
434-443 |
NN |
denotes |
homologue |
T7246 |
418-428 |
JJ |
denotes |
functional |
T7247 |
429-433 |
NN |
denotes |
TACC |
T7248 |
444-446 |
IN |
denotes |
in |
T7249 |
447-452 |
NN |
denotes |
yeast |
T7250 |
452-454 |
, |
denotes |
, |
T7251 |
454-457 |
NN |
denotes |
spc |
T7252 |
457-458 |
HYPH |
denotes |
- |
T7253 |
458-460 |
CD |
denotes |
72 |
T7254 |
460-462 |
, |
denotes |
, |
T7255 |
462-465 |
CC |
denotes |
and |
T7256 |
466-469 |
CD |
denotes |
one |
T7257 |
489-497 |
NN |
denotes |
proteins |
T7258 |
470-472 |
CC |
denotes |
or |
T7259 |
473-477 |
JJR |
denotes |
more |
T7260 |
478-483 |
JJ |
denotes |
human |
T7261 |
484-488 |
NN |
denotes |
TACC |
T7262 |
498-499 |
-LRB- |
denotes |
[ |
T7263 |
499-501 |
CD |
denotes |
21 |
T7264 |
501-502 |
-RRB- |
denotes |
] |
T7265 |
502-503 |
. |
denotes |
. |
T7266 |
503-722 |
sentence |
denotes |
Thus, it is known that all the TACC proteins examined to date interact, via the TACC domain, with the microtubule/centrosomal proteins of the stu2/msps/ch-TOG family [5,6,22-24], and with the Aurora kinases [20,21,25]. |
T7267 |
504-508 |
RB |
denotes |
Thus |
T7268 |
516-521 |
VBN |
denotes |
known |
T7269 |
508-510 |
, |
denotes |
, |
T7270 |
510-512 |
PRP |
denotes |
it |
T7271 |
513-515 |
VBZ |
denotes |
is |
T7272 |
522-526 |
IN |
denotes |
that |
T7273 |
566-574 |
VBP |
denotes |
interact |
T7274 |
527-530 |
PDT |
denotes |
all |
T7275 |
540-548 |
NN |
denotes |
proteins |
T7276 |
531-534 |
DT |
denotes |
the |
T7277 |
535-539 |
NN |
denotes |
TACC |
T7278 |
549-557 |
VBN |
denotes |
examined |
T7279 |
558-560 |
IN |
denotes |
to |
T7280 |
561-565 |
NN |
denotes |
date |
T7281 |
574-576 |
, |
denotes |
, |
T7282 |
576-579 |
IN |
denotes |
via |
T7283 |
580-583 |
DT |
denotes |
the |
T7284 |
589-595 |
NN |
denotes |
domain |
T7285 |
584-588 |
NN |
denotes |
TACC |
T7286 |
595-597 |
, |
denotes |
, |
T7287 |
597-601 |
IN |
denotes |
with |
T7288 |
602-605 |
DT |
denotes |
the |
T7289 |
630-638 |
NN |
denotes |
proteins |
T7290 |
606-617 |
NN |
denotes |
microtubule |
T7291 |
618-629 |
JJ |
denotes |
centrosomal |
T7292 |
617-618 |
HYPH |
denotes |
/ |
T7293 |
639-641 |
IN |
denotes |
of |
T7294 |
642-645 |
DT |
denotes |
the |
T7295 |
663-669 |
NN |
denotes |
family |
T7296 |
646-650 |
NN |
denotes |
stu2 |
T7297 |
650-651 |
HYPH |
denotes |
/ |
T7298 |
651-655 |
NN |
denotes |
msps |
T7299 |
655-656 |
HYPH |
denotes |
/ |
T7300 |
656-658 |
NN |
denotes |
ch |
T7301 |
659-662 |
NN |
denotes |
TOG |
T7302 |
658-659 |
HYPH |
denotes |
- |
T7303 |
670-671 |
-LRB- |
denotes |
[ |
T7304 |
671-672 |
CD |
denotes |
5 |
T7305 |
672-673 |
, |
denotes |
, |
T7306 |
673-674 |
CD |
denotes |
6 |
T7307 |
674-675 |
, |
denotes |
, |
T7308 |
675-677 |
CD |
denotes |
22 |
T7309 |
677-678 |
SYM |
denotes |
- |
T7310 |
678-680 |
CD |
denotes |
24 |
T7311 |
680-681 |
-RRB- |
denotes |
] |
T7312 |
681-683 |
, |
denotes |
, |
T7313 |
683-686 |
CC |
denotes |
and |
T7314 |
687-691 |
IN |
denotes |
with |
T7315 |
692-695 |
DT |
denotes |
the |
T7316 |
703-710 |
NNS |
denotes |
kinases |
T7317 |
696-702 |
NN |
denotes |
Aurora |
T7318 |
711-712 |
-LRB- |
denotes |
[ |
T7319 |
718-720 |
CD |
denotes |
25 |
T7320 |
712-714 |
CD |
denotes |
20 |
T7321 |
714-715 |
, |
denotes |
, |
T7322 |
715-717 |
CD |
denotes |
21 |
T7323 |
717-718 |
, |
denotes |
, |
T7324 |
720-721 |
-RRB- |
denotes |
] |
T7325 |
721-722 |
. |
denotes |
. |
T7326 |
722-854 |
sentence |
denotes |
These interactions are required for the accumulation of the D-TACC, spc72, ceTAC1 and TACC3 proteins to the centrosome [5,6,22-24]. |
T7327 |
723-728 |
DT |
denotes |
These |
T7328 |
729-741 |
NNS |
denotes |
interactions |
T7329 |
746-754 |
VBN |
denotes |
required |
T7330 |
742-745 |
VBP |
denotes |
are |
T7331 |
755-758 |
IN |
denotes |
for |
T7332 |
759-762 |
DT |
denotes |
the |
T7333 |
763-775 |
NN |
denotes |
accumulation |
T7334 |
776-778 |
IN |
denotes |
of |
T7335 |
779-782 |
DT |
denotes |
the |
T7336 |
815-823 |
NN |
denotes |
proteins |
T7337 |
783-784 |
NN |
denotes |
D |
T7338 |
785-789 |
NN |
denotes |
TACC |
T7339 |
784-785 |
HYPH |
denotes |
- |
T7340 |
789-791 |
, |
denotes |
, |
T7341 |
791-796 |
NN |
denotes |
spc72 |
T7342 |
796-798 |
, |
denotes |
, |
T7343 |
798-804 |
NN |
denotes |
ceTAC1 |
T7344 |
805-808 |
CC |
denotes |
and |
T7345 |
809-814 |
NN |
denotes |
TACC3 |
T7346 |
824-826 |
IN |
denotes |
to |
T7347 |
827-830 |
DT |
denotes |
the |
T7348 |
831-841 |
NN |
denotes |
centrosome |
T7349 |
842-843 |
-LRB- |
denotes |
[ |
T7350 |
843-844 |
CD |
denotes |
5 |
T7351 |
844-845 |
, |
denotes |
, |
T7352 |
845-846 |
CD |
denotes |
6 |
T7353 |
846-847 |
, |
denotes |
, |
T7354 |
847-849 |
CD |
denotes |
22 |
T7355 |
849-850 |
SYM |
denotes |
- |
T7356 |
850-852 |
CD |
denotes |
24 |
T7357 |
852-853 |
-RRB- |
denotes |
] |
T7358 |
853-854 |
. |
denotes |
. |
T7359 |
854-1004 |
sentence |
denotes |
Hence, this functional interaction with the centrosome and mitotic spindle is likely to represent the ancient, conserved function of the TACC family. |
T7360 |
855-860 |
RB |
denotes |
Hence |
T7361 |
930-932 |
VBZ |
denotes |
is |
T7362 |
860-862 |
, |
denotes |
, |
T7363 |
862-866 |
DT |
denotes |
this |
T7364 |
878-889 |
NN |
denotes |
interaction |
T7365 |
867-877 |
JJ |
denotes |
functional |
T7366 |
890-894 |
IN |
denotes |
with |
T7367 |
895-898 |
DT |
denotes |
the |
T7368 |
899-909 |
NN |
denotes |
centrosome |
T7369 |
910-913 |
CC |
denotes |
and |
T7370 |
914-921 |
JJ |
denotes |
mitotic |
T7371 |
922-929 |
NN |
denotes |
spindle |
T7372 |
933-939 |
JJ |
denotes |
likely |
T7373 |
940-942 |
TO |
denotes |
to |
T7374 |
943-952 |
VB |
denotes |
represent |
T7375 |
953-956 |
DT |
denotes |
the |
T7376 |
976-984 |
NN |
denotes |
function |
T7377 |
957-964 |
JJ |
denotes |
ancient |
T7378 |
964-966 |
, |
denotes |
, |
T7379 |
966-975 |
VBN |
denotes |
conserved |
T7380 |
985-987 |
IN |
denotes |
of |
T7381 |
988-991 |
DT |
denotes |
the |
T7382 |
997-1003 |
NN |
denotes |
family |
T7383 |
992-996 |
NN |
denotes |
TACC |
T7384 |
1003-1004 |
. |
denotes |
. |
T7385 |
1004-1123 |
sentence |
denotes |
However, it is apparent that the human TACC proteins also differ in their ability to interact with the Aurora kinases. |
T7386 |
1005-1012 |
RB |
denotes |
However |
T7387 |
1017-1019 |
VBZ |
denotes |
is |
T7388 |
1012-1014 |
, |
denotes |
, |
T7389 |
1014-1016 |
PRP |
denotes |
it |
T7390 |
1020-1028 |
JJ |
denotes |
apparent |
T7391 |
1029-1033 |
IN |
denotes |
that |
T7392 |
1063-1069 |
VBP |
denotes |
differ |
T7393 |
1034-1037 |
DT |
denotes |
the |
T7394 |
1049-1057 |
NN |
denotes |
proteins |
T7395 |
1038-1043 |
JJ |
denotes |
human |
T7396 |
1044-1048 |
NN |
denotes |
TACC |
T7397 |
1058-1062 |
RB |
denotes |
also |
T7398 |
1070-1072 |
IN |
denotes |
in |
T7399 |
1073-1078 |
PRP$ |
denotes |
their |
T7400 |
1079-1086 |
NN |
denotes |
ability |
T7401 |
1087-1089 |
TO |
denotes |
to |
T7402 |
1090-1098 |
VB |
denotes |
interact |
T7403 |
1099-1103 |
IN |
denotes |
with |
T7404 |
1104-1107 |
DT |
denotes |
the |
T7405 |
1115-1122 |
NNS |
denotes |
kinases |
T7406 |
1108-1114 |
NN |
denotes |
Aurora |
T7407 |
1122-1123 |
. |
denotes |
. |
T7408 |
1123-1385 |
sentence |
denotes |
For instance, TACC1 and TACC3 interact with Aurora A kinase, whereas TACC2 interacts with Aurora C kinase [21], suggesting a degree of functional specialization in the derivatives of the ancestral chordate TACC, after the radiation of the vertebrate TACC genes. |
T7409 |
1124-1127 |
IN |
denotes |
For |
T7410 |
1154-1162 |
VBP |
denotes |
interact |
T7411 |
1128-1136 |
NN |
denotes |
instance |
T7412 |
1136-1138 |
, |
denotes |
, |
T7413 |
1138-1143 |
NN |
denotes |
TACC1 |
T7414 |
1144-1147 |
CC |
denotes |
and |
T7415 |
1148-1153 |
NN |
denotes |
TACC3 |
T7416 |
1163-1167 |
IN |
denotes |
with |
T7417 |
1168-1174 |
NN |
denotes |
Aurora |
T7418 |
1175-1176 |
NN |
denotes |
A |
T7419 |
1177-1183 |
NN |
denotes |
kinase |
T7420 |
1183-1185 |
, |
denotes |
, |
T7421 |
1185-1192 |
IN |
denotes |
whereas |
T7422 |
1199-1208 |
VBZ |
denotes |
interacts |
T7423 |
1193-1198 |
NN |
denotes |
TACC2 |
T7424 |
1209-1213 |
IN |
denotes |
with |
T7425 |
1214-1220 |
NN |
denotes |
Aurora |
T7426 |
1221-1222 |
NN |
denotes |
C |
T7427 |
1223-1229 |
NN |
denotes |
kinase |
T7428 |
1230-1231 |
-LRB- |
denotes |
[ |
T7429 |
1231-1233 |
CD |
denotes |
21 |
T7430 |
1233-1234 |
-RRB- |
denotes |
] |
T7431 |
1234-1236 |
, |
denotes |
, |
T7432 |
1236-1246 |
VBG |
denotes |
suggesting |
T7433 |
1247-1248 |
DT |
denotes |
a |
T7434 |
1249-1255 |
NN |
denotes |
degree |
T7435 |
1256-1258 |
IN |
denotes |
of |
T7436 |
1259-1269 |
JJ |
denotes |
functional |
T7437 |
1270-1284 |
NN |
denotes |
specialization |
T7438 |
1285-1287 |
IN |
denotes |
in |
T7439 |
1288-1291 |
DT |
denotes |
the |
T7440 |
1292-1303 |
NNS |
denotes |
derivatives |
T7441 |
1304-1306 |
IN |
denotes |
of |
T7442 |
1307-1310 |
DT |
denotes |
the |
T7443 |
1330-1334 |
NN |
denotes |
TACC |
T7444 |
1311-1320 |
JJ |
denotes |
ancestral |
T7445 |
1321-1329 |
NN |
denotes |
chordate |
T7446 |
1334-1336 |
, |
denotes |
, |
T7447 |
1336-1341 |
IN |
denotes |
after |
T7448 |
1342-1345 |
DT |
denotes |
the |
T7449 |
1346-1355 |
NN |
denotes |
radiation |
T7450 |
1356-1358 |
IN |
denotes |
of |
T7451 |
1359-1362 |
DT |
denotes |
the |
T7452 |
1379-1384 |
NNS |
denotes |
genes |
T7453 |
1363-1373 |
NN |
denotes |
vertebrate |
T7454 |
1374-1378 |
NN |
denotes |
TACC |
T7455 |
1384-1385 |
. |
denotes |
. |
R4435 |
T7178 |
T7179 |
det |
The,structure |
R4436 |
T7179 |
T7183 |
nsubj |
structure,suggests |
R4437 |
T7180 |
T7179 |
nmod |
protein,structure |
R4438 |
T7181 |
T7180 |
cc |
and,protein |
R4439 |
T7182 |
T7180 |
conj |
genomic,protein |
R4440 |
T7184 |
T7179 |
prep |
of,structure |
R4441 |
T7185 |
T7186 |
det |
the,members |
R4442 |
T7186 |
T7184 |
pobj |
members,of |
R4443 |
T7187 |
T7188 |
amod |
present,day |
R4444 |
T7188 |
T7186 |
compound |
day,members |
R4445 |
T7189 |
T7190 |
compound |
TACC,family |
R4446 |
T7190 |
T7186 |
compound |
family,members |
R4447 |
T7191 |
T7192 |
mark |
that,mediated |
R4448 |
T7192 |
T7183 |
ccomp |
mediated,suggests |
R4449 |
T7193 |
T7194 |
det |
the,function |
R4450 |
T7194 |
T7192 |
nsubjpass |
function,mediated |
R4451 |
T7195 |
T7194 |
prep |
of,function |
R4452 |
T7196 |
T7197 |
det |
the,protein |
R4453 |
T7197 |
T7195 |
pobj |
protein,of |
R4454 |
T7198 |
T7197 |
amod |
ancestral,protein |
R4455 |
T7199 |
T7197 |
compound |
TACC,protein |
R4456 |
T7200 |
T7192 |
auxpass |
was,mediated |
R4457 |
T7201 |
T7202 |
advmod |
solely,through |
R4458 |
T7202 |
T7192 |
prep |
through,mediated |
R4459 |
T7203 |
T7204 |
det |
the,interactions |
R4460 |
T7204 |
T7202 |
pobj |
interactions,through |
R4461 |
T7205 |
T7204 |
prep |
of,interactions |
R4462 |
T7206 |
T7207 |
det |
the,domain |
R4463 |
T7207 |
T7205 |
pobj |
domain,of |
R4464 |
T7208 |
T7207 |
amod |
conserved,domain |
R4465 |
T7209 |
T7207 |
compound |
TACC,domain |
R4466 |
T7210 |
T7183 |
punct |
.,suggests |
R4467 |
T7212 |
T7213 |
advcl |
Using,predicted |
R4468 |
T7214 |
T7215 |
det |
an,model |
R4469 |
T7215 |
T7212 |
dobj |
model,Using |
R4470 |
T7216 |
T7217 |
advmod |
in,silico |
R4471 |
T7217 |
T7215 |
amod |
silico,model |
R4472 |
T7218 |
T7219 |
compound |
protein,protein |
R4473 |
T7219 |
T7221 |
compound |
protein,interaction |
R4474 |
T7220 |
T7219 |
punct |
-,protein |
R4475 |
T7221 |
T7215 |
compound |
interaction,model |
R4476 |
T7222 |
T7215 |
prep |
based,model |
R4477 |
T7223 |
T7222 |
prep |
upon,based |
R4478 |
T7224 |
T7225 |
amod |
known,components |
R4479 |
T7225 |
T7223 |
pobj |
components,upon |
R4480 |
T7226 |
T7227 |
amod |
mitotic,spindle |
R4481 |
T7227 |
T7225 |
nmod |
spindle,components |
R4482 |
T7228 |
T7227 |
cc |
and,spindle |
R4483 |
T7229 |
T7227 |
conj |
centrosomal,spindle |
R4484 |
T7230 |
T7213 |
punct |
", ",predicted |
R4485 |
T7231 |
T7213 |
nsubj |
we,predicted |
R4486 |
T7232 |
T7213 |
aux |
have,predicted |
R4487 |
T7233 |
T7213 |
advmod |
previously,predicted |
R4488 |
T7234 |
T7235 |
det |
a,number |
R4489 |
T7235 |
T7213 |
dobj |
number,predicted |
R4490 |
T7236 |
T7235 |
prep |
of,number |
R4491 |
T7237 |
T7238 |
amod |
additional,interactions |
R4492 |
T7238 |
T7236 |
pobj |
interactions,of |
R4493 |
T7239 |
T7240 |
dep |
that,conserved |
R4494 |
T7240 |
T7238 |
relcl |
conserved,interactions |
R4495 |
T7241 |
T7240 |
aux |
could,conserved |
R4496 |
T7242 |
T7240 |
auxpass |
be,conserved |
R4497 |
T7243 |
T7240 |
prep |
between,conserved |
R4498 |
T7244 |
T7245 |
det |
a,homologue |
R4499 |
T7245 |
T7243 |
pobj |
homologue,between |
R4500 |
T7246 |
T7245 |
amod |
functional,homologue |
R4501 |
T7247 |
T7245 |
compound |
TACC,homologue |
R4502 |
T7248 |
T7245 |
prep |
in,homologue |
R4503 |
T7249 |
T7248 |
pobj |
yeast,in |
R4504 |
T7250 |
T7245 |
punct |
", ",homologue |
R4505 |
T7251 |
T7245 |
appos |
spc,homologue |
R4506 |
T7252 |
T7251 |
punct |
-,spc |
R4507 |
T7253 |
T7251 |
nummod |
72,spc |
R4508 |
T7254 |
T7245 |
punct |
", ",homologue |
R4509 |
T7255 |
T7245 |
cc |
and,homologue |
R4510 |
T7256 |
T7257 |
nummod |
one,proteins |
R4511 |
T7257 |
T7245 |
conj |
proteins,homologue |
R4512 |
T7258 |
T7256 |
cc |
or,one |
R4513 |
T7259 |
T7256 |
conj |
more,one |
R4514 |
T7260 |
T7257 |
amod |
human,proteins |
R4515 |
T7261 |
T7257 |
compound |
TACC,proteins |
R4516 |
T7262 |
T7263 |
punct |
[,21 |
R4517 |
T7263 |
T7213 |
parataxis |
21,predicted |
R4518 |
T7264 |
T7263 |
punct |
],21 |
R4519 |
T7265 |
T7213 |
punct |
.,predicted |
R4520 |
T7267 |
T7268 |
advmod |
Thus,known |
R4521 |
T7269 |
T7268 |
punct |
", ",known |
R4522 |
T7270 |
T7268 |
nsubjpass |
it,known |
R4523 |
T7271 |
T7268 |
auxpass |
is,known |
R4524 |
T7272 |
T7273 |
mark |
that,interact |
R4525 |
T7273 |
T7268 |
ccomp |
interact,known |
R4526 |
T7274 |
T7275 |
predet |
all,proteins |
R4527 |
T7275 |
T7273 |
nsubj |
proteins,interact |
R4528 |
T7276 |
T7275 |
det |
the,proteins |
R4529 |
T7277 |
T7275 |
compound |
TACC,proteins |
R4530 |
T7278 |
T7275 |
acl |
examined,proteins |
R4531 |
T7279 |
T7278 |
prep |
to,examined |
R4532 |
T7280 |
T7279 |
pobj |
date,to |
R4533 |
T7281 |
T7273 |
punct |
", ",interact |
R4534 |
T7282 |
T7273 |
prep |
via,interact |
R4535 |
T7283 |
T7284 |
det |
the,domain |
R4536 |
T7284 |
T7282 |
pobj |
domain,via |
R4537 |
T7285 |
T7284 |
compound |
TACC,domain |
R4538 |
T7286 |
T7273 |
punct |
", ",interact |
R4539 |
T7287 |
T7273 |
prep |
with,interact |
R4540 |
T7288 |
T7289 |
det |
the,proteins |
R4541 |
T7289 |
T7287 |
pobj |
proteins,with |
R4542 |
T7290 |
T7291 |
npadvmod |
microtubule,centrosomal |
R4543 |
T7291 |
T7289 |
amod |
centrosomal,proteins |
R4544 |
T7292 |
T7291 |
punct |
/,centrosomal |
R4545 |
T7293 |
T7289 |
prep |
of,proteins |
R4546 |
T7294 |
T7295 |
det |
the,family |
R4547 |
T7295 |
T7293 |
pobj |
family,of |
R4548 |
T7296 |
T7295 |
nmod |
stu2,family |
R4549 |
T7297 |
T7296 |
punct |
/,stu2 |
R4550 |
T7298 |
T7296 |
appos |
msps,stu2 |
R4551 |
T7299 |
T7296 |
punct |
/,stu2 |
R4552 |
T7300 |
T7301 |
compound |
ch,TOG |
R4553 |
T7301 |
T7296 |
appos |
TOG,stu2 |
R4554 |
T7302 |
T7301 |
punct |
-,TOG |
R4555 |
T7303 |
T7304 |
punct |
[,5 |
R4556 |
T7304 |
T7289 |
parataxis |
5,proteins |
R4557 |
T7305 |
T7304 |
punct |
",",5 |
R4558 |
T7306 |
T7304 |
appos |
6,5 |
R4559 |
T7307 |
T7304 |
punct |
",",5 |
R4560 |
T7308 |
T7304 |
appos |
22,5 |
R4561 |
T7309 |
T7310 |
punct |
-,24 |
R4562 |
T7310 |
T7308 |
prep |
24,22 |
R4563 |
T7311 |
T7304 |
punct |
],5 |
R4564 |
T7312 |
T7287 |
punct |
", ",with |
R4565 |
T7313 |
T7287 |
cc |
and,with |
R4566 |
T7314 |
T7287 |
conj |
with,with |
R4567 |
T7315 |
T7316 |
det |
the,kinases |
R4568 |
T7316 |
T7314 |
pobj |
kinases,with |
R4569 |
T7317 |
T7316 |
compound |
Aurora,kinases |
R4570 |
T7318 |
T7319 |
punct |
[,25 |
R4571 |
T7319 |
T7316 |
parataxis |
25,kinases |
R4572 |
T7320 |
T7319 |
nummod |
20,25 |
R4573 |
T7321 |
T7319 |
punct |
",",25 |
R4574 |
T7322 |
T7319 |
nummod |
21,25 |
R4575 |
T7323 |
T7319 |
punct |
",",25 |
R4576 |
T7324 |
T7319 |
punct |
],25 |
R4577 |
T7325 |
T7268 |
punct |
.,known |
R4578 |
T7327 |
T7328 |
det |
These,interactions |
R4579 |
T7328 |
T7329 |
nsubjpass |
interactions,required |
R4580 |
T7330 |
T7329 |
auxpass |
are,required |
R4581 |
T7331 |
T7329 |
prep |
for,required |
R4582 |
T7332 |
T7333 |
det |
the,accumulation |
R4583 |
T7333 |
T7331 |
pobj |
accumulation,for |
R4584 |
T7334 |
T7333 |
prep |
of,accumulation |
R4585 |
T7335 |
T7336 |
det |
the,proteins |
R4586 |
T7336 |
T7334 |
pobj |
proteins,of |
R4587 |
T7337 |
T7338 |
nmod |
D,TACC |
R4588 |
T7338 |
T7336 |
nmod |
TACC,proteins |
R4589 |
T7339 |
T7338 |
punct |
-,TACC |
R4590 |
T7340 |
T7338 |
punct |
", ",TACC |
R4591 |
T7341 |
T7338 |
conj |
spc72,TACC |
R4592 |
T7342 |
T7341 |
punct |
", ",spc72 |
R4593 |
T7343 |
T7341 |
conj |
ceTAC1,spc72 |
R4594 |
T7344 |
T7343 |
cc |
and,ceTAC1 |
R4595 |
T7345 |
T7343 |
conj |
TACC3,ceTAC1 |
R4596 |
T7346 |
T7333 |
prep |
to,accumulation |
R4597 |
T7347 |
T7348 |
det |
the,centrosome |
R4598 |
T7348 |
T7346 |
pobj |
centrosome,to |
R4599 |
T7349 |
T7350 |
punct |
[,5 |
R4600 |
T7350 |
T7329 |
parataxis |
5,required |
R4601 |
T7351 |
T7350 |
punct |
",",5 |
R4602 |
T7352 |
T7350 |
appos |
6,5 |
R4603 |
T7353 |
T7350 |
punct |
",",5 |
R4604 |
T7354 |
T7350 |
appos |
22,5 |
R4605 |
T7355 |
T7356 |
punct |
-,24 |
R4606 |
T7356 |
T7354 |
prep |
24,22 |
R4607 |
T7357 |
T7350 |
punct |
],5 |
R4608 |
T7358 |
T7329 |
punct |
.,required |
R4609 |
T7360 |
T7361 |
advmod |
Hence,is |
R4610 |
T7362 |
T7361 |
punct |
", ",is |
R4611 |
T7363 |
T7364 |
det |
this,interaction |
R4612 |
T7364 |
T7361 |
nsubj |
interaction,is |
R4613 |
T7365 |
T7364 |
amod |
functional,interaction |
R4614 |
T7366 |
T7364 |
prep |
with,interaction |
R4615 |
T7367 |
T7368 |
det |
the,centrosome |
R4616 |
T7368 |
T7366 |
pobj |
centrosome,with |
R4617 |
T7369 |
T7368 |
cc |
and,centrosome |
R4618 |
T7370 |
T7371 |
amod |
mitotic,spindle |
R4619 |
T7371 |
T7368 |
conj |
spindle,centrosome |
R4620 |
T7372 |
T7361 |
acomp |
likely,is |
R4621 |
T7373 |
T7374 |
aux |
to,represent |
R4622 |
T7374 |
T7372 |
xcomp |
represent,likely |
R4623 |
T7375 |
T7376 |
det |
the,function |
R4624 |
T7376 |
T7374 |
dobj |
function,represent |
R4625 |
T7377 |
T7376 |
amod |
ancient,function |
R4626 |
T7378 |
T7376 |
punct |
", ",function |
R4627 |
T7379 |
T7376 |
amod |
conserved,function |
R4628 |
T7380 |
T7376 |
prep |
of,function |
R4629 |
T7381 |
T7382 |
det |
the,family |
R4630 |
T7382 |
T7380 |
pobj |
family,of |
R4631 |
T7383 |
T7382 |
compound |
TACC,family |
R4632 |
T7384 |
T7361 |
punct |
.,is |
R4633 |
T7386 |
T7387 |
advmod |
However,is |
R4634 |
T7388 |
T7387 |
punct |
", ",is |
R4635 |
T7389 |
T7387 |
nsubj |
it,is |
R4636 |
T7390 |
T7387 |
acomp |
apparent,is |
R4637 |
T7391 |
T7392 |
mark |
that,differ |
R4638 |
T7392 |
T7387 |
ccomp |
differ,is |
R4639 |
T7393 |
T7394 |
det |
the,proteins |
R4640 |
T7394 |
T7392 |
nsubj |
proteins,differ |
R4641 |
T7395 |
T7394 |
amod |
human,proteins |
R4642 |
T7396 |
T7394 |
compound |
TACC,proteins |
R4643 |
T7397 |
T7392 |
advmod |
also,differ |
R4644 |
T7398 |
T7392 |
prep |
in,differ |
R4645 |
T7399 |
T7400 |
poss |
their,ability |
R4646 |
T7400 |
T7398 |
pobj |
ability,in |
R4647 |
T7401 |
T7402 |
aux |
to,interact |
R4648 |
T7402 |
T7400 |
acl |
interact,ability |
R4649 |
T7403 |
T7402 |
prep |
with,interact |
R4650 |
T7404 |
T7405 |
det |
the,kinases |
R4651 |
T7405 |
T7403 |
pobj |
kinases,with |
R4652 |
T7406 |
T7405 |
compound |
Aurora,kinases |
R4653 |
T7407 |
T7387 |
punct |
.,is |
R4654 |
T7409 |
T7410 |
prep |
For,interact |
R4655 |
T7411 |
T7409 |
pobj |
instance,For |
R4656 |
T7412 |
T7410 |
punct |
", ",interact |
R4657 |
T7413 |
T7410 |
nsubj |
TACC1,interact |
R4658 |
T7414 |
T7413 |
cc |
and,TACC1 |
R4659 |
T7415 |
T7413 |
conj |
TACC3,TACC1 |
R4660 |
T7416 |
T7410 |
prep |
with,interact |
R4661 |
T7417 |
T7418 |
compound |
Aurora,A |
R4662 |
T7418 |
T7419 |
compound |
A,kinase |
R4663 |
T7419 |
T7416 |
pobj |
kinase,with |
R4664 |
T7420 |
T7410 |
punct |
", ",interact |
R4665 |
T7421 |
T7422 |
mark |
whereas,interacts |
R4666 |
T7422 |
T7410 |
advcl |
interacts,interact |
R4667 |
T7423 |
T7422 |
nsubj |
TACC2,interacts |
R4668 |
T7424 |
T7422 |
prep |
with,interacts |
R4669 |
T7425 |
T7426 |
compound |
Aurora,C |
R4670 |
T7426 |
T7427 |
compound |
C,kinase |
R4671 |
T7427 |
T7424 |
pobj |
kinase,with |
R4672 |
T7428 |
T7429 |
punct |
[,21 |
R4673 |
T7429 |
T7422 |
parataxis |
21,interacts |
R4674 |
T7430 |
T7429 |
punct |
],21 |
R4675 |
T7431 |
T7410 |
punct |
", ",interact |
R4676 |
T7432 |
T7410 |
advcl |
suggesting,interact |
R4677 |
T7433 |
T7434 |
det |
a,degree |
R4678 |
T7434 |
T7432 |
dobj |
degree,suggesting |
R4679 |
T7435 |
T7434 |
prep |
of,degree |
R4680 |
T7436 |
T7437 |
amod |
functional,specialization |
R4681 |
T7437 |
T7435 |
pobj |
specialization,of |
R4682 |
T7438 |
T7434 |
prep |
in,degree |
R4683 |
T7439 |
T7440 |
det |
the,derivatives |
R4684 |
T7440 |
T7438 |
pobj |
derivatives,in |
R4685 |
T7441 |
T7440 |
prep |
of,derivatives |
R4686 |
T7442 |
T7443 |
det |
the,TACC |
R4687 |
T7443 |
T7441 |
pobj |
TACC,of |
R4688 |
T7444 |
T7443 |
amod |
ancestral,TACC |
R4689 |
T7445 |
T7443 |
compound |
chordate,TACC |
R4690 |
T7446 |
T7434 |
punct |
", ",degree |
R4691 |
T7447 |
T7434 |
prep |
after,degree |
R4692 |
T7448 |
T7449 |
det |
the,radiation |
R4693 |
T7449 |
T7447 |
pobj |
radiation,after |
R4694 |
T7450 |
T7449 |
prep |
of,radiation |
R4695 |
T7451 |
T7452 |
det |
the,genes |
R4696 |
T7452 |
T7450 |
pobj |
genes,of |
R4697 |
T7453 |
T7452 |
compound |
vertebrate,genes |
R4698 |
T7454 |
T7452 |
compound |
TACC,genes |
R4699 |
T7455 |
T7410 |
punct |
.,interact |