PMC:4331678 / 24038-25058 JSONTXT

{"project":"2_test","denotations":[{"id":"25707434-19435516-14839085","span":{"begin":358,"end":360},"obj":"19435516"}],"text":"We annotated the proteins in each dataset using the recently updated GO term annotation (access date: 2014-05-13) in three sub-ontologies, namely biological process (BP) functions, molecular functions (MF), and cellular component (CC) functions, respectively. Each protein is also annotated with its ancestral function labels. As suggested by Pandey et al. [19], the functional labels which have too few member proteins are not likely to be testable in the wet lab, and thus of no interest to biologists. We retained the function labels which have at least 10 member proteins. In addition, we removed the functional labels that have more than 300 member proteins: these functional labels are too general and their prediction is not as critical as for the others [25,39]. The statistic of these datasets is given in Table 1. In the table, the BP labels are the biological process functions (or terms), the MF labels are the molecular functions, and the CC labels are the cellular component functions in the Gene Ontology."}