PMC:4331676 / 9672-10458 JSONTXT

{"project":"2_test","denotations":[{"id":"25708928-23303794-14842648","span":{"begin":45,"end":47},"obj":"23303794"},{"id":"25708928-23144709-14842648","span":{"begin":45,"end":47},"obj":"23144709"},{"id":"25708928-23395824-14842648","span":{"begin":45,"end":47},"obj":"23395824"},{"id":"25708928-24109555-14842648","span":{"begin":45,"end":47},"obj":"24109555"},{"id":"25708928-24318998-14842648","span":{"begin":45,"end":47},"obj":"24318998"},{"id":"25708928-23029559-14842648","span":{"begin":45,"end":47},"obj":"23029559"},{"id":"25708928-19646926-14842648","span":{"begin":45,"end":47},"obj":"19646926"},{"id":"25708928-19925685-14842648","span":{"begin":45,"end":47},"obj":"19925685"},{"id":"25708928-20955175-14842648","span":{"begin":45,"end":47},"obj":"20955175"},{"id":"25708928-24027761-14842648","span":{"begin":45,"end":47},"obj":"24027761"},{"id":"25708928-23756733-14842648","span":{"begin":45,"end":47},"obj":"23756733"},{"id":"25708928-25016190-14842648","span":{"begin":45,"end":47},"obj":"25016190"},{"id":"25708928-24564479-14842648","span":{"begin":45,"end":47},"obj":"24564479"}],"text":"As shown by a series of recent publications [45-59] and summarized in a comprehensive review, to develop a useful statistical prediction method or model for a biological system, one needs to engage the following procedures: (i) construct or select a valid benchmark dataset to train and test the predictor; (ii) formulate the samples with an effective mathematical expression that can truly reflect their intrinsic correlation with the target to be predicted; (iii) introduce or develop a powerful algorithm (or engine) to operate the prediction; (iv) properly perform cross-validation tests to objectively evaluate the anticipated accuracy of the predictor; (v) construct a web-server for the prediction method. Below, we describe our proposed method followed such a general procedure."}