PMC:4319657 / 81-1125 JSONTXT

{"project":"NEUROSES","denotations":[{"id":"T13","span":{"begin":138,"end":143},"obj":"PATO_0001450"},{"id":"T14","span":{"begin":301,"end":305},"obj":"PATO_0001026"},{"id":"T15","span":{"begin":310,"end":314},"obj":"CHEBI_75830"},{"id":"T16","span":{"begin":672,"end":676},"obj":"PATO_0000469"},{"id":"T17","span":{"begin":686,"end":694},"obj":"CHEBI_35341"},{"id":"T18","span":{"begin":762,"end":767},"obj":"CHEBI_18059"}],"text":"Summary\n\nBackground\nToxic lung injury may manifest itself in many different ways, ranging from respiratory tract irritation and pulmonary edema in severe cases to constrictive bronchiolitis, being a more distant consequence.\nIt is most often the result of accidental exposure to harmful substances at work, at home, or a consequence of industrial disaster.\n\nCase Report\nThis article presents a case of toxic lung injury which occurred after inhalation of legal highs, the so-called “artificial hashish” and at first presented itself radiologically as interstitial pneumonia with pleural effusion and clinically as hypoxemic respiratory insufficiency. After treatment with high doses of steroids, it was histopathologically diagnosed as organizing pneumonia with lipid bodies.\n\nConclusions\nDue to the lack of pathognomonic radiological images for toxic lung injury, information on possible etiology of irritants is very important. As novel psychoactive substances appeared in Europe, they should be considered as the cause of toxic lung injury. "}

{"project":"BLAH2015_Annotations_test_5","denotations":[{"id":"T2","span":{"begin":301,"end":305},"obj":"PATO_0001026"},{"id":"T3","span":{"begin":310,"end":314},"obj":"CHEBI_75830"},{"id":"T4","span":{"begin":672,"end":676},"obj":"PATO_0000469"},{"id":"T5","span":{"begin":686,"end":694},"obj":"CHEBI_35341"},{"id":"T6","span":{"begin":762,"end":767},"obj":"CHEBI_18059"},{"id":"T7","span":{"begin":983,"end":987},"obj":"Patient"},{"id":"T319","span":{"begin":983,"end":987},"obj":"Patient"}],"text":"Summary\n\nBackground\nToxic lung injury may manifest itself in many different ways, ranging from respiratory tract irritation and pulmonary edema in severe cases to constrictive bronchiolitis, being a more distant consequence.\nIt is most often the result of accidental exposure to harmful substances at work, at home, or a consequence of industrial disaster.\n\nCase Report\nThis article presents a case of toxic lung injury which occurred after inhalation of legal highs, the so-called “artificial hashish” and at first presented itself radiologically as interstitial pneumonia with pleural effusion and clinically as hypoxemic respiratory insufficiency. After treatment with high doses of steroids, it was histopathologically diagnosed as organizing pneumonia with lipid bodies.\n\nConclusions\nDue to the lack of pathognomonic radiological images for toxic lung injury, information on possible etiology of irritants is very important. As novel psychoactive substances appeared in Europe, they should be considered as the cause of toxic lung injury. "}