PMC:4277126 / 40951-41761 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4277126","sourcedb":"PMC","sourceid":"4277126","source_url":"http://www.ncbi.nlm.nih.gov/pmc/4277126","text":"Clinical study of LBPs in cancer patients\nIn a clinical trial, 79 patients with advanced cancer were treated with lymphokine-activated killer (LAK)/IL-2 in combination with LBPs.54 Initial results indicated that objective regression of cancer was achieved in patients with malignant melanoma, renal cell carcinoma, colorectal carcinoma, lung cancer, nasopharyngeal carcinoma, and malignant hydrothorax. The response rate of patients treated with LAK/IL-2 plus LBPs was higher than that of patients treated with LAK/IL-2 alone.54 The mean remission in patients treated with LAK/IL-2 plus LBPs also lasted significantly longer. LAK/IL-2 plus LBP treatment led to more marked increase in natural killer (NK) and LAK cell activity than LAK/IL-2 alone.54 LBPs may be used as an adjuvant in the biotherapy of cancer.","divisions":[{"label":"Title","span":{"begin":0,"end":41}}],"tracks":[{"project":"2_test","denotations":[{"id":"25552899-7720497-26094242","span":{"begin":178,"end":180},"obj":"7720497"},{"id":"25552899-7720497-26094243","span":{"begin":526,"end":528},"obj":"7720497"},{"id":"25552899-7720497-26094244","span":{"begin":747,"end":749},"obj":"7720497"}],"attributes":[{"subj":"25552899-7720497-26094242","pred":"source","obj":"2_test"},{"subj":"25552899-7720497-26094243","pred":"source","obj":"2_test"},{"subj":"25552899-7720497-26094244","pred":"source","obj":"2_test"}]},{"project":"NEUROSES","denotations":[{"id":"T743","span":{"begin":416,"end":420},"obj":"PATO_0000161"},{"id":"T744","span":{"begin":416,"end":420},"obj":"PATO_0001470"},{"id":"T745","span":{"begin":654,"end":657},"obj":"CHEBI_43739"},{"id":"T746","span":{"begin":666,"end":672},"obj":"PATO_0000465"},{"id":"T747","span":{"begin":773,"end":781},"obj":"CHEBI_60809"},{"id":"T742","span":{"begin":80,"end":88},"obj":"PATO_0000694"}],"attributes":[{"subj":"T743","pred":"source","obj":"NEUROSES"},{"subj":"T744","pred":"source","obj":"NEUROSES"},{"subj":"T745","pred":"source","obj":"NEUROSES"},{"subj":"T746","pred":"source","obj":"NEUROSES"},{"subj":"T747","pred":"source","obj":"NEUROSES"},{"subj":"T742","pred":"source","obj":"NEUROSES"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#ecde93","default":true},{"id":"NEUROSES","color":"#c493ec"}]}]}}