PMC:4277126 / 142932-143576 JSONTXT

{"project":"2_test","denotations":[{"id":"25552899-22500431-26094499","span":{"begin":15,"end":18},"obj":"22500431"},{"id":"25552899-22500431-26094500","span":{"begin":641,"end":644},"obj":"22500431"}],"text":"Aging\nWei et al182 studied the protective mechanism of LBP administration for 30 days on the function of ovarian tissue in 14-month-old female senile rats. Radioimmunoassay was used to determine the blood levels of estrone and progesterone, and enzyme immunoassay was used to determine the ovarian levels of IGF-1. Daily oral LBPs (20 mg/kg, 40 mg/kg, or 60 mg/kg body weight) for 30 days significantly recovered uterine atrophy and restored serum IGF-1 level, estrone and progesterone levels that were decreased in older rats, and reduced the expression of IGF-binding protein-1 (IGFBP-1) in ovarian tissue that was increased in older rats.182"}

{"project":"NEUROSES","denotations":[{"id":"T2974","span":{"begin":93,"end":101},"obj":"PATO_0000173"},{"id":"T2975","span":{"begin":132,"end":135},"obj":"PATO_0000308"},{"id":"T2976","span":{"begin":136,"end":142},"obj":"PATO_0000383"},{"id":"T2977","span":{"begin":215,"end":222},"obj":"CHEBI_17263"},{"id":"T2978","span":{"begin":461,"end":468},"obj":"CHEBI_17263"},{"id":"T2979","span":{"begin":227,"end":239},"obj":"CHEBI_17026"},{"id":"T2980","span":{"begin":473,"end":485},"obj":"CHEBI_17026"},{"id":"T2981","span":{"begin":369,"end":375},"obj":"PATO_0000128"},{"id":"T2983","span":{"begin":503,"end":512},"obj":"PATO_0001997"},{"id":"T2984","span":{"begin":532,"end":539},"obj":"PATO_0001997"},{"id":"T2985","span":{"begin":570,"end":577},"obj":"CHEBI_16541"},{"id":"T2986","span":{"begin":570,"end":577},"obj":"CHEBI_36080"},{"id":"T2987","span":{"begin":617,"end":626},"obj":"PATO_0000470"}],"text":"Aging\nWei et al182 studied the protective mechanism of LBP administration for 30 days on the function of ovarian tissue in 14-month-old female senile rats. Radioimmunoassay was used to determine the blood levels of estrone and progesterone, and enzyme immunoassay was used to determine the ovarian levels of IGF-1. Daily oral LBPs (20 mg/kg, 40 mg/kg, or 60 mg/kg body weight) for 30 days significantly recovered uterine atrophy and restored serum IGF-1 level, estrone and progesterone levels that were decreased in older rats, and reduced the expression of IGF-binding protein-1 (IGFBP-1) in ovarian tissue that was increased in older rats.182"}