PMC:4277126 / 137571-138480 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4277126","sourcedb":"PMC","sourceid":"4277126","source_url":"http://www.ncbi.nlm.nih.gov/pmc/4277126","text":"Bisphenol A-induced sperimatogenic damage\nLBPs showed protected effects against spermatogenic injuries induced by bisphenol A in mice.177 Bisphenol A was subcutaneously injected into mice at a dose of 20 mg/kg body weight for 7 consecutive days and LBPs were administered simultaneously with bisphenol A by gavage daily for 7 days. The results showed that the weights of testis and epididymis were all increased after supplementation with different dosages of LBPs compared with bisphenol A alone group, and the activities of SOD and GPx were significantly increased in LBP-treated groups, while MDA contents were gradually decreased.177 LBPs also showed significant positive effects on the expression of Bcl-2/Bax in bisphenol A-treated mice. The authors concluded that LBPs might be one of the potential ingredients protecting the adult male animals from bisphenol A-induced reproductive damage (Figure 15).","divisions":[{"label":"Title","span":{"begin":0,"end":41}}],"tracks":[{"project":"2_test","denotations":[{"id":"25552899-24454506-26094486","span":{"begin":134,"end":137},"obj":"24454506"},{"id":"25552899-24454506-26094487","span":{"begin":634,"end":637},"obj":"24454506"}],"attributes":[{"subj":"25552899-24454506-26094486","pred":"source","obj":"2_test"},{"subj":"25552899-24454506-26094487","pred":"source","obj":"2_test"}]},{"project":"NEUROSES","denotations":[{"id":"T2869","span":{"begin":35,"end":41},"obj":"PATO_0001020"},{"id":"T2870","span":{"begin":890,"end":896},"obj":"PATO_0001020"},{"id":"T2871","span":{"begin":215,"end":221},"obj":"PATO_0000128"},{"id":"T2872","span":{"begin":402,"end":411},"obj":"PATO_0000470"},{"id":"T2873","span":{"begin":557,"end":566},"obj":"PATO_0000470"},{"id":"T2874","span":{"begin":497,"end":502},"obj":"CHEBI_24433"},{"id":"T2875","span":{"begin":596,"end":599},"obj":"CHEBI_566274"},{"id":"T2876","span":{"begin":624,"end":633},"obj":"PATO_0001997"},{"id":"T2877","span":{"begin":839,"end":843},"obj":"PATO_0000384"},{"id":"T2878","span":{"begin":839,"end":843},"obj":"CHEBI_30780"}],"attributes":[{"subj":"T2869","pred":"source","obj":"NEUROSES"},{"subj":"T2870","pred":"source","obj":"NEUROSES"},{"subj":"T2871","pred":"source","obj":"NEUROSES"},{"subj":"T2872","pred":"source","obj":"NEUROSES"},{"subj":"T2873","pred":"source","obj":"NEUROSES"},{"subj":"T2874","pred":"source","obj":"NEUROSES"},{"subj":"T2875","pred":"source","obj":"NEUROSES"},{"subj":"T2876","pred":"source","obj":"NEUROSES"},{"subj":"T2877","pred":"source","obj":"NEUROSES"},{"subj":"T2878","pred":"source","obj":"NEUROSES"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#df93ec","default":true},{"id":"NEUROSES","color":"#93ecc5"}]}]}}