PMC:4195273 / 15118-15975
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4195273","sourcedb":"PMC","sourceid":"4195273","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4195273","text":"Present in both classic neuroendocrine neurons and hypothalamic projection neurons, Arc CART displays an almost 100% colocalization with POMC and complete segregation from the more medially located orexigenic NPY in rodents (Elias et al., 1998; Vrang et al., 1999a; Fekete et al., 2000, 2004). The co-existence of CART with POMC and derivatives such as α-MSH were found to persist throughout the rostrocaudal extent of the Arc (Vrang et al., 1999a), wherein CART immunoreactivity (IR) was depicted in a separate study to pervade all α-MSH-IR perikarya and axons (Menyhért et al., 2007), which accords with the anorectic role widely adopted for POMC/CART neurons. In accordance with established neuronal projections from Arc (Schwartz et al., 2000), all α-MSH-IR axons in the PVN have also been shown to contain CART immunoreactivity (Menyhért et al., 2007).","tracks":[{"project":"TEST0","denotations":[{"id":"25352770-231-239-357365","span":{"begin":239,"end":243},"obj":"[\"9883730\"]"},{"id":"25352770-234-242-357367","span":{"begin":281,"end":285},"obj":"[\"11125000\"]"},{"id":"25352770-223-231-357368","span":{"begin":287,"end":291},"obj":"[\"14730586\"]"},{"id":"25352770-235-243-357370","span":{"begin":580,"end":584},"obj":"[\"17525122\"]"},{"id":"25352770-79-87-357371","span":{"begin":742,"end":746},"obj":"[\"10766253\"]"},{"id":"25352770-188-196-357372","span":{"begin":851,"end":855},"obj":"[\"17525122\"]"}],"attributes":[{"subj":"25352770-231-239-357365","pred":"source","obj":"TEST0"},{"subj":"25352770-234-242-357367","pred":"source","obj":"TEST0"},{"subj":"25352770-223-231-357368","pred":"source","obj":"TEST0"},{"subj":"25352770-235-243-357370","pred":"source","obj":"TEST0"},{"subj":"25352770-79-87-357371","pred":"source","obj":"TEST0"},{"subj":"25352770-188-196-357372","pred":"source","obj":"TEST0"}]},{"project":"0_colil","denotations":[{"id":"25352770-9883730-357365","span":{"begin":239,"end":243},"obj":"9883730"},{"id":"25352770-11125000-357367","span":{"begin":281,"end":285},"obj":"11125000"},{"id":"25352770-14730586-357368","span":{"begin":287,"end":291},"obj":"14730586"},{"id":"25352770-17525122-357370","span":{"begin":580,"end":584},"obj":"17525122"},{"id":"25352770-10766253-357371","span":{"begin":742,"end":746},"obj":"10766253"},{"id":"25352770-17525122-357372","span":{"begin":851,"end":855},"obj":"17525122"}],"attributes":[{"subj":"25352770-9883730-357365","pred":"source","obj":"0_colil"},{"subj":"25352770-11125000-357367","pred":"source","obj":"0_colil"},{"subj":"25352770-14730586-357368","pred":"source","obj":"0_colil"},{"subj":"25352770-17525122-357370","pred":"source","obj":"0_colil"},{"subj":"25352770-10766253-357371","pred":"source","obj":"0_colil"},{"subj":"25352770-17525122-357372","pred":"source","obj":"0_colil"}]},{"project":"2_test","denotations":[{"id":"25352770-9883730-38284354","span":{"begin":239,"end":243},"obj":"9883730"},{"id":"25352770-11125000-38284356","span":{"begin":281,"end":285},"obj":"11125000"},{"id":"25352770-14730586-38284357","span":{"begin":287,"end":291},"obj":"14730586"},{"id":"25352770-17525122-38284359","span":{"begin":580,"end":584},"obj":"17525122"},{"id":"25352770-10766253-38284360","span":{"begin":742,"end":746},"obj":"10766253"},{"id":"25352770-17525122-38284361","span":{"begin":851,"end":855},"obj":"17525122"}],"attributes":[{"subj":"25352770-9883730-38284354","pred":"source","obj":"2_test"},{"subj":"25352770-11125000-38284356","pred":"source","obj":"2_test"},{"subj":"25352770-14730586-38284357","pred":"source","obj":"2_test"},{"subj":"25352770-17525122-38284359","pred":"source","obj":"2_test"},{"subj":"25352770-10766253-38284360","pred":"source","obj":"2_test"},{"subj":"25352770-17525122-38284361","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"TEST0","color":"#ece493","default":true},{"id":"0_colil","color":"#ca93ec"},{"id":"2_test","color":"#93ecb0"}]}]}}