PMC:4161609 / 2361-3211
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4161609","sourcedb":"PMC","sourceid":"4161609","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4161609","text":"Pharmacological treatment is the mainstay of management for most patients with asthma. Guideline-based management results in significant improvement in health-related quality of life in most patients.1 Although the goal of therapy is to control asthma by reducing impairment and risk, many patients seem to continue to have some asthma symptoms, such as cough, phlegm, or dyspnea, when asked about their symptoms on a questionnaire.2 Some important complications that occur with asthma, such as rhinitis,3 sinusitis,4,5 and gastroesophageal reflux disease (GERD),6 are known to affect asthma symptoms. These complications may make bronchial inflammation worse, because asthma symptoms are mainly caused by airway inflammation. Whether these complications directly affect the intensity of bronchial inflammation continues to be an unanswered question.","tracks":[{"project":"2_test","denotations":[{"id":"25228816-17050557-55570422","span":{"begin":200,"end":201},"obj":"17050557"},{"id":"25228816-22449663-55570423","span":{"begin":432,"end":433},"obj":"22449663"},{"id":"25228816-21781135-55570424","span":{"begin":504,"end":505},"obj":"21781135"},{"id":"25228816-10478602-55570425","span":{"begin":516,"end":517},"obj":"10478602"},{"id":"25228816-8705638-55570426","span":{"begin":518,"end":519},"obj":"8705638"},{"id":"25228816-19118263-55570427","span":{"begin":563,"end":564},"obj":"19118263"}],"attributes":[{"subj":"25228816-17050557-55570422","pred":"source","obj":"2_test"},{"subj":"25228816-22449663-55570423","pred":"source","obj":"2_test"},{"subj":"25228816-21781135-55570424","pred":"source","obj":"2_test"},{"subj":"25228816-10478602-55570425","pred":"source","obj":"2_test"},{"subj":"25228816-8705638-55570426","pred":"source","obj":"2_test"},{"subj":"25228816-19118263-55570427","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#aeec93","default":true}]}]}}