PMC:4159494 / 28213-28632 JSONTXT

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Resistance exercise can also be used as an effective intervention to improve BMD; however, the precise physiological actions that modulate bone remodeling are not clearly understood. Although beyond the scope of this review, some potential mechanism of action involve mechanical mechanotransduction [90, 91], production of nitric oxide (NO) as a result of mechanical loading [92–94], and prostaglandin release [92, 95].