PMC:4159494 / 13176-14065 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4159494","sourcedb":"PMC","sourceid":"4159494","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4159494","text":"As the prevalence of elderly individuals increases in the USA and throughout the world, so does the prevalence of sarcopenia and osteopenia/osteoporosis. The addition of obesity to these existing conditions exacerbates the metabolic abnormalities likely leading to reduced physical function and quality of life. Osteosarcopenic obesity represents a change in paradigm that has gone unrecognized until recently, due to the lack of accurate technology to assess human body composition, as sophisticated tools are needed to accurately assess fat, lean, and bone tissue compartments. Furthermore, as suggested by Stenholm et al. [43], although in healthy young and older individuals bone and muscle change concurrently with changes in body weight, this process may be impaired in some individuals when the excess of body weight occurs without concurrent increases in bone and muscle mass [43].","tracks":[]}