PMC:4159490 / 4165-6031 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4159490","sourcedb":"PMC","sourceid":"4159490","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4159490","text":"Study participants\nInclusion criteria for MHD patients were as follows: (1) age, ≥18 years; (2) MHD vintage, ≥6 months; (3) MHD treatment, thrice weekly; (4) no hospitalizations during the previous 3 months, except for vascular access repair; (5) no amputations or prostheses in lower extremities; (6) able to ambulate and ability to complete all study protocol tests and wear the physical activity monitor for 10 days; and (7) good compliance to study protocol. Exclusion criteria included the following: (1) any acute infectious or other inflammatory illnesses, (2) active cancer except basal cell carcinoma, (3) myocardial infarction or angina pectoris within the past 12 months, and (4) current heart or lung failure or severe liver disease.\nAll but four MHD patients were recruited from two DaVita Corporation-owned chronic dialysis centers in the South Bay area of Los Angeles County. At the time of study, these two centers were treating 335 MHD patients. In order to increase the number of diabetic MHD patients, four MHD patients with diabetic nephropathy who satisfied the entry criteria were recruited from two additional DaVita chronic dialysis centers. Normal controls were of similar age range and gender distribution and had no known acute or chronic systemic illnesses or disorders of the extremities that could impede mobility or other physical activities. Normal controls were recruited from the South Bay area of Los Angeles County through their church affiliation. To our knowledge, no normal volunteers engaged in regular sports activities. The authors certify that they comply with the ethical guidelines for authorship and publishing of the Journal of Cachexia, Sarcopenia and Muscle. This study was approved by the IRB of the Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center. All subjects gave informed written consent.","divisions":[{"label":"title","span":{"begin":0,"end":18}},{"label":"p","span":{"begin":19,"end":745}}],"tracks":[]}