PMC:4157143 / 17658-18235 JSONTXT

Annnotations TAB JSON ListView MergeView

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4157143","sourcedb":"PMC","sourceid":"4157143","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4157143","text":"We obtained annotations (missense, synonymous, regulatory, and splice region) by using the Variant Effect Predictor tool,35 which queries annotation from the Ensembl website. ENCODE transcription factor (TF) binding and DNase I hypersensitivity peaks were obtained from RegulomeDB.24 Conservation scores obtained from PhyloP36 (phyloP100way) software were downloaded from the UCSC Genome Browser. Motif-disrupting sites were downloaded from HaploReg (v.2).37 Variant allele frequency was based on phase 1 of the 1000 Genomes Project38 as calculated across European populations.","tracks":[{"project":"2_test","denotations":[{"id":"25192044-20562413-2055633","span":{"begin":121,"end":123},"obj":"20562413"},{"id":"25192044-22955989-2055634","span":{"begin":281,"end":283},"obj":"22955989"},{"id":"25192044-15965027-2055635","span":{"begin":324,"end":326},"obj":"15965027"},{"id":"25192044-22064851-2055636","span":{"begin":456,"end":458},"obj":"22064851"},{"id":"25192044-23128226-2055637","span":{"begin":532,"end":534},"obj":"23128226"}],"attributes":[{"subj":"25192044-20562413-2055633","pred":"source","obj":"2_test"},{"subj":"25192044-22955989-2055634","pred":"source","obj":"2_test"},{"subj":"25192044-15965027-2055635","pred":"source","obj":"2_test"},{"subj":"25192044-22064851-2055636","pred":"source","obj":"2_test"},{"subj":"25192044-23128226-2055637","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#93ec9c","default":true}]}]}}