PMC:4156421 / 24152-24936 JSONTXT

{"project":"2_test","denotations":[{"id":"25192356-23001799-90446789","span":{"begin":195,"end":197},"obj":"23001799"}],"text":"The patient's somewhat acute presentation following onset of flu-like symptoms is perhaps consistent with an antecedent viral infection, which is a setting in which NSIP has been known to occur [34]. In principle, genomic sequence analysis could permit identification of pathogens that might have triggered putative immune responses and ultimately set the stage for development of fibrotic lung disease. The DNA sequence read mapping strategy we pursued here, involving alignment to a reference genome, filters away the DNA sequences of other organisms. Moreover, for reason of convenience, DNA was extracted from liver, prior to embalming, whereas DNA extraction from lung tissue or regional lymph nodes would have served better for the purpose of detecting the genomes of pathogens."}