PMC:4143611 / 22218-23351 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4143611","sourcedb":"PMC","sourceid":"4143611","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4143611","text":"We propose the application of rigorous post-surgical monitoring to patients with CD who have been treated with TSS. Education of endocrinologists on this matter has begun with Bertagna and Guignat’s recent publication on the approach to the diagnosis and treatment of persistence and recurrent CD [48]. The authors highlight the available tests and therapeutic avenues, including combination therapies that can be used to treat a patient not cured by primary TSS. Based on our own clinical experiences and understanding of the literature, we have proposed what we believe is a feasible algorithm for post-surgical follow-up monitoring. The algorithm represents our recommendations for post-surgical monitoring of patients with CD and is presented with the caveat that it is designed to be a general guide rather than a simple protocol. Treatment decisions can be complex and must be made on a case-by-case basis using all available information, including levels of biochemical markers, severity of disease, the evolving availability of medical therapies, and patient concerns and preferences in cases of persistent hypercortisolemia.","tracks":[{"project":"2_test","denotations":[{"id":"24980037-23564942-63233455","span":{"begin":298,"end":300},"obj":"23564942"}],"attributes":[{"subj":"24980037-23564942-63233455","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#ec9693","default":true}]}]}}