PMC:4143611 / 21311-22217 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4143611","sourcedb":"PMC","sourceid":"4143611","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4143611","text":"Despite the large number of long-term follow-up studies published, no single positive predictive factor of recurrence has emerged. Although subnormal levels of early morning serum cortisol levels measured within a few days following surgery suggest a lower risk of recurrence, relapse does occur in approximately 9 % of patients in this population [40]. Patients who achieve normal, but not subnormal post-surgical levels of cortisol are at a higher risk for recurrence (~24 %), although many of these patients may experience long-term remission [40]. Evaluation of the HPA axis in addition to cortisol levels may provide an advantage, but results to date are contradictory and further studies are needed. Since there is no fail-safe predictor of recurrence, standardized lifelong monitoring of post-surgical patients with CD is recommended for timely detection and optimal treatment of disease recurrence.","tracks":[{"project":"2_test","denotations":[{"id":"24980037-20651632-63233453","span":{"begin":349,"end":351},"obj":"20651632"},{"id":"24980037-20651632-63233454","span":{"begin":547,"end":549},"obj":"20651632"}],"attributes":[{"subj":"24980037-20651632-63233453","pred":"source","obj":"2_test"},{"subj":"24980037-20651632-63233454","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#ecae93","default":true}]}]}}