PMC:4143611 / 1911-2313 JSONTXT

{"project":"2_test","denotations":[{"id":"24980037-22728347-63233394","span":{"begin":399,"end":400},"obj":"22728347"}],"text":"Cushing’s disease (CD), a rare illness characterized by chronic hypercortisolemia secondary to the overproduction of adrenocorticotropic hormone (ACTH) by a pituitary adenoma, is associated with high risk of developing serious complications such as diabetes mellitus, cardiovascular disease, and depression, and a mortality rate between 1.7- and 4.8-fold higher than that of the general population [1]."}