PMC:4143611 / 17970-18476 JSONTXT

{"project":"2_test","denotations":[{"id":"24980037-21918830-63233448","span":{"begin":275,"end":277},"obj":"21918830"}],"text":"We propose that early morning serum cortisol levels of patients in immediate remission be monitored at semiannual intervals for 3 years. This recommendation is based on the finding that the highest rates of recurrence are observed within approximately 5 years following TSS [27]. If no elevation is observed within 3 years, monitoring frequency can be tapered to an annual basis. However, patients should be strongly encouraged to return for testing sooner if symptoms of CD begin to reappear at any point."}