PMC:4143611 / 10257-11195 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4143611","sourcedb":"PMC","sourceid":"4143611","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4143611","text":"Surprisingly, SCS is not a term used to call attention to the subtle hypercortisolemia commonly observed following adenomectomy for CD. Furthermore, to the best of our knowledge, there are no controlled studies focusing on the consequences of subtle or intermittent hypercortisolism in patients who have undergone surgery. This knowledge gap may, in part, be as a result of difficulties inherent to the diagnosis of mild forms of CD in the early post-operative period. Similarly, the lack of a standardized approach to evaluate the HPA axis in patients with CD following surgery may be partially due to the inconsistency and unreliability of diagnostic tests under different circumstances or severity of disease. This phenomenon, or spectrum effect, is used to emphasize this concept in which the sensitivity and specificity of tests are not fixed, but rather vary with the severity or temporal state of the disease being considered [37].","tracks":[]}