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{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4137170","sourcedb":"PMC","sourceid":"4137170","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4137170","text":"The hyaluronic acid that was used for this study underwent hydroexpansivity by binding with water molecules [22], and it could be expand thoroughly on the defect area by contact with blood or tissue fluid when it was injected into the bone defect. Moreover, unlike slow degrading hydroxyapatite, the ability of the fast degrading TCP results in the release of calcium ions. Therefore, TCP is known for its osteoinductive ability to trigger the signaling pathway through protein kinase C pathways and promote the gene expression of BMPs [23–25].","tracks":[{"project":"2_test","denotations":[{"id":"24928668-21123283-61779600","span":{"begin":109,"end":111},"obj":"21123283"},{"id":"24928668-20643969-61779601","span":{"begin":537,"end":539},"obj":"20643969"},{"id":"24928668-22285104-61779601","span":{"begin":537,"end":539},"obj":"22285104"}],"attributes":[{"subj":"24928668-21123283-61779600","pred":"source","obj":"2_test"},{"subj":"24928668-20643969-61779601","pred":"source","obj":"2_test"},{"subj":"24928668-22285104-61779601","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"2_test","color":"#b8ec93","default":true}]}]}}