PMC:4137170 / 17657-19089 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4137170","sourcedb":"PMC","sourceid":"4137170","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4137170","text":"The micro-CT results for the implant group revealed a scanty amount of newly formed bone around the fixture in the marrow space. The hydrogel group showed some newly formed bone around the fixture, but the amount was negligible. On the other hand, the BMP-2 group showed excellent osseointegration between the cortical bone and the implant and newly formed bone was identified in the marrow space around the fixture (Fig. 6). The bone-to-implant contact ratio within the fixture pitch of the implant group and the hydrogel group were 6.93 ± 3.8 % (n = 20) and 4.90 ± 7.8 % (n = 20), respectively. By comparison, the ratio for the BMP-2 group was 18.5 ± 10.1 % (n = 20) and this value was significantly higher than that of the other two groups (P = 0.0043 and 0.0001 for the implant group and the hydrogel group, respectively).\nFig. 6 Micro-CT results. a Only a dental implant fixture was implanted (implant group); b A composite of the β-TCP microspheres and the hyaluronic acid powder gel was injected and a dental implant fixture was inserted (hydrogel group); c A composite of the rhBMP-2 loaded β-TCP microspheres and the hyaluronic acid powder gel was injected and a dental implant fixture was inserted (BMP-2 group). In panel a, new bone formation was insignificant around the implant fixture but some new bone was shown in panel b, while extensive new bone formation was observed in panel c (arrows: newly formed bony tissue)","divisions":[{"label":"label","span":{"begin":827,"end":833}}],"tracks":[]}