PMC:4136538 / 29307-29765 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4136538","sourcedb":"PMC","sourceid":"4136538","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4136538","text":"In summary, our data support that lumbar spinal cord infiltrating Th1, and not Th2, CD4+ T lymphocytes mediate the maintenance of peripheral nerve injury-induced neuropathic pain. These infiltrating Th1 CD4+ T lymphocytes are likely to mediate their effects in mechanisms involving multiple Th1 cytokines and glial activation. Further investigation of CD4+ T lymphocyte-mediated pathways may result in novel, more efficacious treatments for neuropathic pain.","tracks":[]}