PMC:4134656 / 6702-7767 JSONTXT

{"project":"2_test","denotations":[{"id":"25136206-23266923-58659534","span":{"begin":695,"end":696},"obj":"23266923"}],"text":"Once a decision has been made to treat the haemangioma, pre-treatment investigations should be tailored to the chosen therapeutic modality. Before initiating propranolol therapy, the children need to be assessed for the following contraindications: bronchial asthma, heart failure, sinus bradycardia, hypoglycaemia, hypotension, heart block and known allergy to propranolol. The initial examination should include a thorough cardiopulmonary assessment including pulse rate, blood pressure and blood sugar. A baseline electrocardiogram (ECG) is usually recommended. Although echocardiography is not a routine investigation, it may be required to exclude functional and structural heart diseases.[7] The pre-treatment work-up before starting steroid therapy include ruling out active infection or primary immunodeficiency disease, (complete blood count with differential leucocyte count, serum biochemistry, chest x-ray and urine and stool microscopy), and a baseline anthropometric examination (height, weight) and blood pressure, which should be monitored serially."}