PMC:4134656 / 35167-36219
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4134656","sourcedb":"PMC","sourceid":"4134656","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4134656","text":"IH are the most common benign vascular tumours. They are a cause of parental discomfort and anxiety and need to be carefully assessed from the treatment point of view. Most IH are uncomplicated and can be managed by active non-intervention alone. However, the recent encouraging reports of topical timolol in haemangiomas suggest that it can be advised even for uncomplicated localized lesions to accelerate the involution process. Systemic steroids have been considered the therapeutic mainstay for complicated haemangiomas for several decades. Recently, there have been several studies describing the efficacy and safety of propranolol in treating infantile haemangiomas. Though comparative studies between steroids and propranolol are few, a good therapeutic efficacy, even in the post-proliferation phase and a better side-effect profile has tilted the balance in favour of propranolol. Only future prospective trials involving a larger number of patients and a longer follow-up period will tell whether propranolol fulfils its therapeutic promise.","tracks":[]}