PMC:4129401 / 39680-40475 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/4129401","sourcedb":"PMC","sourceid":"4129401","source_url":"https://www.ncbi.nlm.nih.gov/pmc/4129401","text":"Figure 2 Clinical Presentation of Subjects with POC1B Mutations\n(A and B) Fundus photography of the right eye of individual A-II:3 of family A at 12 years of age. (A) Posterior pole with normal macular region. (B) Peripheral field with relative hypopigmentation (∗), but no pathologic RPE changes.\n(C and D) Fundus photography of the right eye of individual B-II:1 of family B at 60 years of age. (C) Posterior pole with optic nerve pallor (∗), attenuated vessels (arrowhead), and no RPE disturbances at the macula. (D) Peripheral inferior field with mild RPE atrophy and bone-spicule pigmentations (arrowhead).\n(E) OCT of the left eye of individual B-II:1 showed no foveal hypoplasia but did show changes at the inner-segment ellipsoid zone (arrow) and adherent posterior hyaloid membrane (∗).","divisions":[{"label":"label","span":{"begin":0,"end":8}},{"label":"p","span":{"begin":10,"end":64}},{"label":"p","span":{"begin":65,"end":298}},{"label":"p","span":{"begin":299,"end":612}}],"tracks":[]}