PMC:4129400 / 1697-2183 JSONTXT

{"project":"2_test","denotations":[{"id":"25087611-18846087-2046300","span":{"begin":166,"end":167},"obj":"18846087"},{"id":"25087611-20981092-2046300","span":{"begin":166,"end":167},"obj":"20981092"},{"id":"25087611-24074859-2046300","span":{"begin":166,"end":167},"obj":"24074859"},{"id":"25087611-22955986-2046301","span":{"begin":346,"end":347},"obj":"22955986"},{"id":"25087611-23183705-2046301","span":{"begin":346,"end":347},"obj":"23183705"},{"id":"25087611-18398418-2046301","span":{"begin":346,"end":347},"obj":"18398418"}],"text":"Our ability to sequence genomes at an ever-increasing rate has resulted in the identification of many new common and rare genetic variants across human populations.1–3 Much effort has been devoted to identifying relationships between genetic variation and complex human phenotypes, including susceptibility to disease and adverse drug response.4–6 Developing a mechanistic biological understanding of such statistical associations represents a major ongoing challenge in human genomics."}