PMC:4047574 / 9666-10574 JSONTXT

{"project":"2_test","denotations":[{"id":"24914308-11900821-83979727","span":{"begin":99,"end":101},"obj":"11900821"},{"id":"T150","span":{"begin":99,"end":101},"obj":"11900821"}],"text":"Open-field test\nThe open-field test was performed according to the method described by Papp et al.[20] with modifications and was carried out before stress, 2 weeks after stress and 4 weeks after stress. The open-field apparatus was a four-sided 100 cm × 100 cm × 40 cm wooden enclosure, with floor painted white and divided into 25 equal squares by black lines and side walls painted black. Tests were conducted in a darkened, quiet room lit by a 60-W light bulb suspended above the center of the open field. Each rat was gently placed onto the middle square of the open-field apparatus facing away from an observer and allowed to explore freely. The number of crossing sector lines with all four paws and the number of rearings on its hind limbs were recorded during a test period of 3 min. After each animal was tested, the test apparatus was cleaned with a detergent to eliminate odors for the next test."}