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PMC:400732 / 113-1110 JSONTXT

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Id Subject Object Predicate Lexical cue
T250 0-8 NN denotes Dopamine
T251 9-19 NN denotes modulation
T252 88-90 VBZ denotes is
T253 20-22 IN denotes of
T254 23-31 JJ denotes neuronal
T255 32-41 NN denotes signaling
T256 42-44 IN denotes in
T257 45-48 DT denotes the
T258 57-63 NN denotes cortex
T259 49-56 JJ denotes frontal
T260 63-65 , denotes ,
T261 65-73 NN denotes midbrain
T262 73-75 , denotes ,
T263 75-78 CC denotes and
T264 79-87 NN denotes striatum
T265 91-100 JJ denotes essential
T266 101-104 IN denotes for
T267 105-115 VBG denotes processing
T268 116-119 CC denotes and
T269 120-131 VBG denotes integrating
T270 132-139 JJ denotes diverse
T271 157-164 NNS denotes stimuli
T272 140-148 JJ denotes external
T273 149-156 JJ denotes sensory
T274 165-168 CC denotes and
T275 169-178 VBG denotes attaching
T276 179-187 NN denotes salience
T277 188-190 IN denotes to
T278 191-204 JJ denotes environmental
T279 205-209 NNS denotes cues
T280 210-214 WDT denotes that
T281 215-221 VBP denotes signal
T282 222-228 JJ denotes causal
T283 229-242 NNS denotes relationships
T284 242-244 , denotes ,
T285 244-251 RB denotes thereby
T286 252-259 VBG denotes guiding
T287 260-264 NN denotes goal
T288 265-273 VBN denotes directed
T289 264-265 HYPH denotes -
T290 285-294 NNS denotes behaviors
T291 273-275 , denotes ,
T292 275-284 JJ denotes adaptable
T293 294-295 . denotes .
T294 295-387 sentence denotes At the cellular level, dopamine signaling is mediated through D1-like or D2-like receptors.
T295 296-298 IN denotes At
T296 341-349 VBN denotes mediated
T297 299-302 DT denotes the
T298 312-317 NN denotes level
T299 303-311 JJ denotes cellular
T300 317-319 , denotes ,
T301 319-327 NN denotes dopamine
T302 328-337 NN denotes signaling
T303 338-340 VBZ denotes is
T304 350-357 IN denotes through
T305 358-360 NN denotes D1
T306 361-365 JJ denotes like
T307 360-361 HYPH denotes -
T308 377-386 NNS denotes receptors
T309 366-368 CC denotes or
T310 369-371 NN denotes D2
T311 372-376 JJ denotes like
T312 371-372 HYPH denotes -
T313 386-387 . denotes .
T314 387-560 sentence denotes Although a role for D1-like receptors in a variety of goal-directed behaviors has been identified, an explicit involvement of D2 receptors has not been clearly established.
T315 388-396 IN denotes Although
T316 475-485 VBN denotes identified
T317 397-398 DT denotes a
T318 399-403 NN denotes role
T319 404-407 IN denotes for
T320 408-410 NN denotes D1
T321 411-415 JJ denotes like
T322 410-411 HYPH denotes -
T323 416-425 NNS denotes receptors
T324 426-428 IN denotes in
T325 429-430 DT denotes a
T326 431-438 NN denotes variety
T327 439-441 IN denotes of
T328 442-446 NN denotes goal
T329 447-455 VBN denotes directed
T330 446-447 HYPH denotes -
T331 456-465 NNS denotes behaviors
T332 466-469 VBZ denotes has
T333 470-474 VBN denotes been
T334 548-559 VBN denotes established
T335 485-487 , denotes ,
T336 487-489 DT denotes an
T337 499-510 NN denotes involvement
T338 490-498 JJ denotes explicit
T339 511-513 IN denotes of
T340 514-516 NN denotes D2
T341 517-526 NNS denotes receptors
T342 527-530 VBZ denotes has
T343 531-534 RB denotes not
T344 535-539 VBN denotes been
T345 540-547 RB denotes clearly
T346 559-560 . denotes .
T347 560-997 sentence denotes To determine whether dopamine D2 receptor-mediated signaling contributes to associative and reversal learning, we compared C57Bl/6J mice that completely lack functional dopamine D2 receptors to wild-type mice with respect to their ability to attach appropriate salience to external stimuli (stimulus discrimination) and disengage from inappropriate behavioral strategies when reinforcement contingencies change (e.g. reversal learning).
T348 561-563 TO denotes To
T349 564-573 VB denotes determine
T350 675-683 VBD denotes compared
T351 574-581 IN denotes whether
T352 622-633 VBZ denotes contributes
T353 582-590 NN denotes dopamine
T354 591-593 NN denotes D2
T355 594-602 NN denotes receptor
T356 603-611 VBN denotes mediated
T357 602-603 HYPH denotes -
T358 612-621 NN denotes signaling
T359 634-636 IN denotes to
T360 637-648 JJ denotes associative
T361 662-670 NN denotes learning
T362 649-652 CC denotes and
T363 653-661 JJ denotes reversal
T364 670-672 , denotes ,
T365 672-674 PRP denotes we
T366 684-689 NN denotes C57Bl
T367 690-692 NN denotes 6J
T368 689-690 HYPH denotes /
T369 693-697 NNS denotes mice
T370 698-702 WDT denotes that
T371 714-718 VBP denotes lack
T372 703-713 RB denotes completely
T373 719-729 JJ denotes functional
T374 742-751 NNS denotes receptors
T375 730-738 NN denotes dopamine
T376 739-741 NN denotes D2
T377 752-754 IN denotes to
T378 755-759 JJ denotes wild
T379 760-764 NN denotes type
T380 759-760 HYPH denotes -
T381 765-769 NNS denotes mice
T382 770-774 IN denotes with
T383 775-782 NN denotes respect
T384 783-785 IN denotes to
T385 786-791 PRP$ denotes their
T386 792-799 NN denotes ability
T387 800-802 TO denotes to
T388 803-809 VB denotes attach
T389 810-821 JJ denotes appropriate
T390 822-830 NN denotes salience
T391 831-833 IN denotes to
T392 834-842 JJ denotes external
T393 843-850 NNS denotes stimuli
T394 851-852 -LRB- denotes (
T395 861-875 NN denotes discrimination
T396 852-860 NN denotes stimulus
T397 875-876 -RRB- denotes )
T398 877-880 CC denotes and
T399 881-890 VB denotes disengage
T400 891-895 IN denotes from
T401 896-909 JJ denotes inappropriate
T402 921-931 NNS denotes strategies
T403 910-920 JJ denotes behavioral
T404 932-936 WRB denotes when
T405 965-971 VBP denotes change
T406 937-950 NN denotes reinforcement
T407 951-964 NNS denotes contingencies
T408 972-973 -LRB- denotes (
T409 987-995 NN denotes learning
T410 973-977 FW denotes e.g.
T411 978-986 NN denotes reversal
T412 995-996 -RRB- denotes )
T413 996-997 . denotes .
R21 T250 T251 compound Dopamine,modulation
R22 T251 T252 nsubj modulation,is
R23 T253 T251 prep of,modulation
R24 T254 T255 amod neuronal,signaling
R25 T255 T253 pobj signaling,of
R26 T256 T251 prep in,modulation
R27 T257 T258 det the,cortex
R28 T258 T256 pobj cortex,in
R29 T259 T258 amod frontal,cortex
R30 T260 T258 punct ", ",cortex
R31 T261 T258 conj midbrain,cortex
R32 T262 T261 punct ", ",midbrain
R33 T263 T261 cc and,midbrain
R34 T264 T261 conj striatum,midbrain
R35 T265 T252 acomp essential,is
R36 T266 T252 prep for,is
R37 T267 T266 pcomp processing,for
R38 T268 T267 cc and,processing
R39 T269 T267 conj integrating,processing
R40 T270 T271 amod diverse,stimuli
R41 T271 T269 dobj stimuli,integrating
R42 T272 T271 amod external,stimuli
R43 T273 T271 amod sensory,stimuli
R44 T274 T267 cc and,processing
R45 T275 T267 conj attaching,processing
R46 T276 T275 dobj salience,attaching
R47 T277 T275 prep to,attaching
R48 T278 T279 amod environmental,cues
R49 T279 T277 pobj cues,to
R50 T280 T281 dep that,signal
R51 T281 T279 relcl signal,cues
R52 T282 T283 amod causal,relationships
R53 T283 T281 dobj relationships,signal
R54 T284 T275 punct ", ",attaching
R55 T285 T286 advmod thereby,guiding
R56 T286 T275 advcl guiding,attaching
R57 T287 T288 npadvmod goal,directed
R58 T288 T290 amod directed,behaviors
R59 T289 T288 punct -,directed
R60 T290 T286 dobj behaviors,guiding
R61 T291 T290 punct ", ",behaviors
R62 T292 T290 amod adaptable,behaviors
R63 T293 T252 punct .,is
R64 T295 T296 prep At,mediated
R65 T297 T298 det the,level
R66 T298 T295 pobj level,At
R67 T299 T298 amod cellular,level
R68 T300 T296 punct ", ",mediated
R69 T301 T302 compound dopamine,signaling
R70 T302 T296 nsubjpass signaling,mediated
R71 T303 T296 auxpass is,mediated
R72 T304 T296 prep through,mediated
R73 T305 T306 npadvmod D1,like
R74 T306 T308 amod like,receptors
R75 T307 T306 punct -,like
R76 T308 T304 pobj receptors,through
R77 T309 T306 cc or,like
R78 T310 T311 npadvmod D2,like
R79 T311 T306 conj like,like
R80 T312 T311 punct -,like
R81 T313 T296 punct .,mediated
R82 T315 T316 mark Although,identified
R83 T316 T334 advcl identified,established
R84 T317 T318 det a,role
R85 T318 T316 nsubjpass role,identified
R86 T319 T318 prep for,role
R87 T320 T321 npadvmod D1,like
R88 T321 T323 amod like,receptors
R89 T322 T321 punct -,like
R90 T323 T319 pobj receptors,for
R91 T324 T318 prep in,role
R92 T325 T326 det a,variety
R93 T326 T324 pobj variety,in
R94 T327 T326 prep of,variety
R95 T328 T329 npadvmod goal,directed
R96 T329 T331 amod directed,behaviors
R97 T330 T329 punct -,directed
R98 T331 T327 pobj behaviors,of
R99 T332 T316 aux has,identified
R100 T333 T316 auxpass been,identified
R101 T335 T334 punct ", ",established
R102 T336 T337 det an,involvement
R103 T337 T334 nsubjpass involvement,established
R104 T338 T337 amod explicit,involvement
R105 T339 T337 prep of,involvement
R106 T340 T341 compound D2,receptors
R107 T341 T339 pobj receptors,of
R108 T342 T334 aux has,established
R109 T343 T334 neg not,established
R110 T344 T334 auxpass been,established
R111 T345 T334 advmod clearly,established
R112 T346 T334 punct .,established
R113 T348 T349 aux To,determine
R114 T349 T350 advcl determine,compared
R115 T351 T352 mark whether,contributes
R116 T352 T349 ccomp contributes,determine
R117 T353 T354 compound dopamine,D2
R118 T354 T355 compound D2,receptor
R119 T355 T356 npadvmod receptor,mediated
R120 T356 T358 amod mediated,signaling
R121 T357 T356 punct -,mediated
R122 T358 T352 nsubj signaling,contributes
R123 T359 T352 prep to,contributes
R124 T360 T361 amod associative,learning
R125 T361 T359 pobj learning,to
R126 T362 T360 cc and,associative
R127 T363 T360 conj reversal,associative
R128 T364 T350 punct ", ",compared
R129 T365 T350 nsubj we,compared
R130 T366 T367 compound C57Bl,6J
R131 T367 T369 compound 6J,mice
R132 T368 T367 punct /,6J
R133 T369 T350 dobj mice,compared
R134 T370 T371 dep that,lack
R135 T371 T369 relcl lack,mice
R136 T372 T371 advmod completely,lack
R137 T373 T374 amod functional,receptors
R138 T374 T371 dobj receptors,lack
R139 T375 T376 compound dopamine,D2
R140 T376 T374 compound D2,receptors
R141 T377 T350 prep to,compared
R142 T378 T379 amod wild,type
R143 T379 T381 compound type,mice
R144 T380 T379 punct -,type
R145 T381 T377 pobj mice,to
R146 T382 T350 prep with,compared
R147 T383 T382 pobj respect,with
R148 T384 T383 prep to,respect
R149 T385 T386 poss their,ability
R150 T386 T384 pobj ability,to
R151 T387 T388 aux to,attach
R152 T388 T386 acl attach,ability
R153 T389 T390 amod appropriate,salience
R154 T390 T388 dobj salience,attach
R155 T391 T388 prep to,attach
R156 T392 T393 amod external,stimuli
R157 T393 T391 pobj stimuli,to
R158 T394 T395 punct (,discrimination
R159 T395 T388 parataxis discrimination,attach
R160 T396 T395 compound stimulus,discrimination
R161 T397 T395 punct ),discrimination
R162 T398 T388 cc and,attach
R163 T399 T388 conj disengage,attach
R164 T400 T399 prep from,disengage
R165 T401 T402 amod inappropriate,strategies
R166 T402 T400 pobj strategies,from
R167 T403 T402 amod behavioral,strategies
R168 T404 T405 advmod when,change
R169 T405 T399 advcl change,disengage
R170 T406 T407 compound reinforcement,contingencies
R171 T407 T405 nsubj contingencies,change
R172 T408 T409 punct (,learning
R173 T409 T399 parataxis learning,disengage
R174 T410 T409 advmod e.g.,learning
R175 T411 T409 compound reversal,learning
R176 T412 T409 punct ),learning
R177 T413 T350 punct .,compared

craft-ca-core-ex-dev

Below, discontinuous spans are shown in the bag model. You can change it to the chain model.

Id Subject Object Predicate Lexical cue
T149 0-8 CHEBI:18243 denotes Dopamine
T150 9-19 GO:0065007 denotes modulation
T151 23-31 CL:0000540 denotes neuronal
T152 32-41 GO_EXT:cell_communication_or_signaling_or_signal_transduction denotes signaling
T153 49-63 UBERON:0001870 denotes frontal cortex
T154 65-73 UBERON:0001891 denotes midbrain
T155 79-87 UBERON:0002435 denotes striatum
T156 149-156 GO_EXT:detection_or_sensing_of_stimulus denotes sensory
T157 252-259 GO_EXT:biological_direction_or_guidance denotes guiding
T158 265-273 GO_EXT:biological_direction_or_guidance denotes directed
T159 275-294 GO:0051867 denotes adaptable behaviors
T160 303-311 CL_GO_EXT:cell denotes cellular
T161 319-327 CHEBI:18243 denotes dopamine
T162 319-337 GO:0007212 denotes dopamine signaling
T164 358-365,377-386 PR_EXT:000001107 denotes D1-like receptors
T165 369-386 PR_EXT:000001108 denotes D2-like receptors
T166 377-386 GO_EXT:0004872 denotes receptors
T167 408-425 PR_EXT:000001107 denotes D1-like receptors
T168 416-425 GO_EXT:0004872 denotes receptors
T169 447-455 GO_EXT:biological_direction_or_guidance denotes directed
T170 456-465 GO_PATO_EXT:biological_behavior denotes behaviors
T171 514-526 PR_EXT:000001177 denotes D2 receptors
T172 517-526 GO_EXT:0004872 denotes receptors
T173 582-590 CHEBI:18243 denotes dopamine
T174 582-602 PR_EXT:000001177 denotes dopamine D2 receptor
T175 594-602 GO_EXT:0004872 denotes receptor
T176 612-621 GO_EXT:cell_communication_or_signaling_or_signal_transduction denotes signaling
T178 637-648,662-670 GO:0008306 denotes associative learning
T179 693-697 NCBITaxon:10088 denotes mice
T180 730-738 CHEBI:18243 denotes dopamine
T181 730-751 PR_EXT:000001177 denotes dopamine D2 receptors
T182 742-751 GO_EXT:0004872 denotes receptors
T183 755-764 SO_EXT:wild_type_entity_or_quality denotes wild-type
T184 765-769 NCBITaxon:10088 denotes mice
T185 910-920 GO_PATO_EXT:biological_behavior denotes behavioral
T186 987-995 GO:0007612 denotes learning

craft-ca-core-dev

Below, discontinuous spans are shown in the bag model. You can change it to the chain model.

Id Subject Object Predicate Lexical cue
T91 0-8 CHEBI:18243 denotes Dopamine
T92 9-19 GO:0065007 denotes modulation
T93 23-31 CL:0000540 denotes neuronal
T94 49-63 UBERON:0001870 denotes frontal cortex
T95 65-73 UBERON:0001891 denotes midbrain
T96 79-87 UBERON:0002435 denotes striatum
T97 275-294 GO:0051867 denotes adaptable behaviors
T98 319-327 CHEBI:18243 denotes dopamine
T99 319-337 GO:0007212 denotes dopamine signaling
T101 358-365,377-386 PR:000001107 denotes D1-like receptors
T102 369-386 PR:000001108 denotes D2-like receptors
T103 408-425 PR:000001107 denotes D1-like receptors
T104 514-526 PR:000001177 denotes D2 receptors
T105 582-590 CHEBI:18243 denotes dopamine
T106 582-602 PR:000001177 denotes dopamine D2 receptor
T108 637-648,662-670 GO:0008306 denotes associative learning
T109 693-697 NCBITaxon:10088 denotes mice
T110 730-738 CHEBI:18243 denotes dopamine
T111 730-751 PR:000001177 denotes dopamine D2 receptors
T112 765-769 NCBITaxon:10088 denotes mice
T113 987-995 GO:0007612 denotes learning