Id |
Subject |
Object |
Predicate |
Lexical cue |
T452 |
0-7 |
NNS |
denotes |
Results |
T453 |
7-159 |
sentence |
denotes |
Mice deficient in Abcg8 have significantly increased plasma and tissue plant sterol levels (sitosterol and campesterol) consistent with sitosterolemia. |
T454 |
8-12 |
NNS |
denotes |
Mice |
T455 |
32-36 |
VBP |
denotes |
have |
T456 |
13-22 |
JJ |
denotes |
deficient |
T457 |
23-25 |
IN |
denotes |
in |
T458 |
26-31 |
NN |
denotes |
Abcg8 |
T459 |
37-50 |
RB |
denotes |
significantly |
T460 |
51-60 |
VBN |
denotes |
increased |
T461 |
61-67 |
NN |
denotes |
plasma |
T462 |
68-71 |
CC |
denotes |
and |
T463 |
72-78 |
NN |
denotes |
tissue |
T464 |
85-91 |
NN |
denotes |
sterol |
T465 |
79-84 |
NN |
denotes |
plant |
T466 |
92-98 |
NNS |
denotes |
levels |
T467 |
99-100 |
-LRB- |
denotes |
( |
T468 |
100-110 |
NN |
denotes |
sitosterol |
T469 |
111-114 |
CC |
denotes |
and |
T470 |
115-126 |
NN |
denotes |
campesterol |
T471 |
126-127 |
-RRB- |
denotes |
) |
T472 |
128-138 |
JJ |
denotes |
consistent |
T473 |
139-143 |
IN |
denotes |
with |
T474 |
144-158 |
NN |
denotes |
sitosterolemia |
T475 |
158-159 |
. |
denotes |
. |
T476 |
159-312 |
sentence |
denotes |
Interestingly, Abcg5/sterolin-1 was expressed in both liver and intestine in Abcg8/sterolin-2 deficient mice and continued to show an apical expression. |
T477 |
160-173 |
RB |
denotes |
Interestingly |
T478 |
196-205 |
VBN |
denotes |
expressed |
T479 |
173-175 |
, |
denotes |
, |
T480 |
175-180 |
NN |
denotes |
Abcg5 |
T481 |
181-189 |
NN |
denotes |
sterolin |
T482 |
180-181 |
HYPH |
denotes |
/ |
T483 |
189-190 |
HYPH |
denotes |
- |
T484 |
190-191 |
CD |
denotes |
1 |
T485 |
192-195 |
VBD |
denotes |
was |
T486 |
206-208 |
IN |
denotes |
in |
T487 |
209-213 |
CC |
denotes |
both |
T488 |
214-219 |
NN |
denotes |
liver |
T489 |
220-223 |
CC |
denotes |
and |
T490 |
224-233 |
NN |
denotes |
intestine |
T491 |
234-236 |
IN |
denotes |
in |
T492 |
237-242 |
NN |
denotes |
Abcg8 |
T493 |
243-251 |
NN |
denotes |
sterolin |
T494 |
242-243 |
HYPH |
denotes |
/ |
T495 |
254-263 |
JJ |
denotes |
deficient |
T496 |
251-252 |
HYPH |
denotes |
- |
T497 |
252-253 |
CD |
denotes |
2 |
T498 |
264-268 |
NNS |
denotes |
mice |
T499 |
269-272 |
CC |
denotes |
and |
T500 |
273-282 |
VBD |
denotes |
continued |
T501 |
283-285 |
TO |
denotes |
to |
T502 |
286-290 |
VB |
denotes |
show |
T503 |
291-293 |
DT |
denotes |
an |
T504 |
301-311 |
NN |
denotes |
expression |
T505 |
294-300 |
JJ |
denotes |
apical |
T506 |
311-312 |
. |
denotes |
. |
T507 |
312-459 |
sentence |
denotes |
Remarkably, Abcg8 deficient mice had an impaired ability to secrete cholesterol into bile, but still maintained the ability to secrete sitosterol. |
T508 |
313-323 |
RB |
denotes |
Remarkably |
T509 |
346-349 |
VBD |
denotes |
had |
T510 |
323-325 |
, |
denotes |
, |
T511 |
325-330 |
NN |
denotes |
Abcg8 |
T512 |
331-340 |
JJ |
denotes |
deficient |
T513 |
341-345 |
NNS |
denotes |
mice |
T514 |
350-352 |
DT |
denotes |
an |
T515 |
362-369 |
NN |
denotes |
ability |
T516 |
353-361 |
JJ |
denotes |
impaired |
T517 |
370-372 |
TO |
denotes |
to |
T518 |
373-380 |
VB |
denotes |
secrete |
T519 |
381-392 |
NN |
denotes |
cholesterol |
T520 |
393-397 |
IN |
denotes |
into |
T521 |
398-402 |
NN |
denotes |
bile |
T522 |
402-404 |
, |
denotes |
, |
T523 |
404-407 |
CC |
denotes |
but |
T524 |
408-413 |
RB |
denotes |
still |
T525 |
414-424 |
VBD |
denotes |
maintained |
T526 |
425-428 |
DT |
denotes |
the |
T527 |
429-436 |
NN |
denotes |
ability |
T528 |
437-439 |
TO |
denotes |
to |
T529 |
440-447 |
VB |
denotes |
secrete |
T530 |
448-458 |
NN |
denotes |
sitosterol |
T531 |
458-459 |
. |
denotes |
. |
T532 |
459-646 |
sentence |
denotes |
We also report an intermediate phenotype in the heterozygous Abcg8+/- mice that are not sitosterolemic, but have a decreased level of biliary sterol secretion relative to wild-type mice. |
T533 |
460-462 |
PRP |
denotes |
We |
T534 |
468-474 |
VBP |
denotes |
report |
T535 |
463-467 |
RB |
denotes |
also |
T536 |
475-477 |
DT |
denotes |
an |
T537 |
491-500 |
NN |
denotes |
phenotype |
T538 |
478-490 |
JJ |
denotes |
intermediate |
T539 |
501-503 |
IN |
denotes |
in |
T540 |
504-507 |
DT |
denotes |
the |
T541 |
530-534 |
NNS |
denotes |
mice |
T542 |
508-520 |
JJ |
denotes |
heterozygous |
T543 |
521-526 |
NN |
denotes |
Abcg8 |
T544 |
526-527 |
SYM |
denotes |
+ |
T545 |
527-528 |
HYPH |
denotes |
/ |
T546 |
528-529 |
SYM |
denotes |
- |
T547 |
535-539 |
WDT |
denotes |
that |
T548 |
540-543 |
VBP |
denotes |
are |
T549 |
544-547 |
RB |
denotes |
not |
T550 |
548-562 |
JJ |
denotes |
sitosterolemic |
T551 |
562-564 |
, |
denotes |
, |
T552 |
564-567 |
CC |
denotes |
but |
T553 |
568-572 |
VBP |
denotes |
have |
T554 |
573-574 |
DT |
denotes |
a |
T555 |
585-590 |
NN |
denotes |
level |
T556 |
575-584 |
VBN |
denotes |
decreased |
T557 |
591-593 |
IN |
denotes |
of |
T558 |
594-601 |
JJ |
denotes |
biliary |
T559 |
609-618 |
NN |
denotes |
secretion |
T560 |
602-608 |
NN |
denotes |
sterol |
T561 |
619-627 |
JJ |
denotes |
relative |
T562 |
628-630 |
IN |
denotes |
to |
T563 |
631-635 |
JJ |
denotes |
wild |
T564 |
636-640 |
NN |
denotes |
type |
T565 |
635-636 |
HYPH |
denotes |
- |
T566 |
641-645 |
NNS |
denotes |
mice |
T567 |
645-646 |
. |
denotes |
. |
R175 |
T454 |
T455 |
nsubj |
Mice,have |
R176 |
T456 |
T454 |
amod |
deficient,Mice |
R177 |
T457 |
T454 |
prep |
in,Mice |
R178 |
T458 |
T457 |
pobj |
Abcg8,in |
R179 |
T459 |
T460 |
advmod |
significantly,increased |
R180 |
T460 |
T461 |
amod |
increased,plasma |
R181 |
T461 |
T455 |
dobj |
plasma,have |
R182 |
T462 |
T461 |
cc |
and,plasma |
R183 |
T463 |
T464 |
compound |
tissue,sterol |
R184 |
T464 |
T466 |
compound |
sterol,levels |
R186 |
T466 |
T461 |
conj |
levels,plasma |
R187 |
T467 |
T461 |
punct |
(,plasma |
R188 |
T468 |
T461 |
appos |
sitosterol,plasma |
R189 |
T469 |
T468 |
cc |
and,sitosterol |
R190 |
T470 |
T468 |
conj |
campesterol,sitosterol |
R191 |
T471 |
T461 |
punct |
),plasma |
R192 |
T472 |
T461 |
amod |
consistent,plasma |
R193 |
T473 |
T472 |
prep |
with,consistent |
R194 |
T474 |
T473 |
pobj |
sitosterolemia,with |
R195 |
T475 |
T455 |
punct |
.,have |
R196 |
T477 |
T478 |
advmod |
Interestingly,expressed |
R197 |
T479 |
T478 |
punct |
", ",expressed |
R198 |
T480 |
T481 |
compound |
Abcg5,sterolin |
R199 |
T481 |
T478 |
nsubjpass |
sterolin,expressed |
R201 |
T483 |
T481 |
punct |
-,sterolin |
R202 |
T484 |
T481 |
nummod |
1,sterolin |
R203 |
T485 |
T478 |
auxpass |
was,expressed |
R204 |
T486 |
T478 |
prep |
in,expressed |
R205 |
T487 |
T488 |
preconj |
both,liver |
R206 |
T488 |
T486 |
pobj |
liver,in |
R207 |
T489 |
T488 |
cc |
and,liver |
R208 |
T490 |
T488 |
conj |
intestine,liver |
R209 |
T491 |
T478 |
prep |
in,expressed |
R210 |
T492 |
T493 |
compound |
Abcg8,sterolin |
R211 |
T493 |
T495 |
npadvmod |
sterolin,deficient |
R213 |
T495 |
T498 |
amod |
deficient,mice |
R216 |
T498 |
T491 |
pobj |
mice,in |
R217 |
T499 |
T478 |
cc |
and,expressed |
R218 |
T500 |
T478 |
conj |
continued,expressed |
R219 |
T501 |
T502 |
aux |
to,show |
R220 |
T502 |
T500 |
xcomp |
show,continued |
R221 |
T503 |
T504 |
det |
an,expression |
R222 |
T504 |
T502 |
dobj |
expression,show |
R224 |
T506 |
T478 |
punct |
.,expressed |
R225 |
T508 |
T509 |
advmod |
Remarkably,had |
R226 |
T510 |
T509 |
punct |
", ",had |
R227 |
T511 |
T512 |
npadvmod |
Abcg8,deficient |
R228 |
T512 |
T513 |
amod |
deficient,mice |
R229 |
T513 |
T509 |
nsubj |
mice,had |
R230 |
T514 |
T515 |
det |
an,ability |
R231 |
T515 |
T509 |
dobj |
ability,had |
R233 |
T517 |
T518 |
aux |
to,secrete |
R234 |
T518 |
T515 |
acl |
secrete,ability |
R235 |
T519 |
T518 |
dobj |
cholesterol,secrete |
R236 |
T520 |
T518 |
prep |
into,secrete |
R237 |
T521 |
T520 |
pobj |
bile,into |
R238 |
T522 |
T509 |
punct |
", ",had |
R239 |
T523 |
T509 |
cc |
but,had |
R240 |
T524 |
T525 |
advmod |
still,maintained |
R241 |
T525 |
T509 |
conj |
maintained,had |
R242 |
T526 |
T527 |
det |
the,ability |
R243 |
T527 |
T525 |
dobj |
ability,maintained |
R244 |
T528 |
T529 |
aux |
to,secrete |
R245 |
T529 |
T527 |
acl |
secrete,ability |
R246 |
T530 |
T529 |
dobj |
sitosterol,secrete |
R247 |
T531 |
T509 |
punct |
.,had |
R248 |
T533 |
T534 |
nsubj |
We,report |
R249 |
T535 |
T534 |
advmod |
also,report |
R250 |
T536 |
T537 |
det |
an,phenotype |
R251 |
T537 |
T534 |
dobj |
phenotype,report |
R253 |
T539 |
T537 |
prep |
in,phenotype |
R254 |
T540 |
T541 |
det |
the,mice |
R255 |
T541 |
T539 |
pobj |
mice,in |
R261 |
T547 |
T548 |
dep |
that,are |
R262 |
T548 |
T541 |
relcl |
are,mice |
R263 |
T549 |
T548 |
neg |
not,are |
R264 |
T550 |
T548 |
acomp |
sitosterolemic,are |
R265 |
T551 |
T548 |
punct |
", ",are |
R266 |
T552 |
T548 |
cc |
but,are |
R267 |
T553 |
T548 |
conj |
have,are |
R268 |
T554 |
T555 |
det |
a,level |
R269 |
T555 |
T553 |
dobj |
level,have |
R271 |
T557 |
T555 |
prep |
of,level |
R272 |
T558 |
T559 |
amod |
biliary,secretion |
R273 |
T559 |
T557 |
pobj |
secretion,of |
R275 |
T561 |
T553 |
advcl |
relative,have |
R276 |
T562 |
T561 |
prep |
to,relative |
R277 |
T563 |
T564 |
amod |
wild,type |
R278 |
T564 |
T566 |
compound |
type,mice |
R280 |
T566 |
T562 |
pobj |
mice,to |
R281 |
T567 |
T534 |
punct |
.,report |
R223 |
T505 |
T504 |
amod |
apical,expression |
R232 |
T516 |
T515 |
amod |
impaired,ability |
R252 |
T538 |
T537 |
amod |
intermediate,phenotype |
R256 |
T542 |
T541 |
amod |
heterozygous,mice |
R257 |
T543 |
T541 |
nmod |
Abcg8,mice |
R258 |
T544 |
T543 |
punct |
+,Abcg8 |
R259 |
T545 |
T543 |
punct |
/,Abcg8 |
R260 |
T546 |
T543 |
punct |
-,Abcg8 |
R270 |
T556 |
T555 |
amod |
decreased,level |
R274 |
T560 |
T559 |
compound |
sterol,secretion |
R279 |
T565 |
T564 |
punct |
-,type |
R185 |
T465 |
T464 |
compound |
plant,sterol |
R200 |
T482 |
T481 |
punct |
/,sterolin |
R212 |
T494 |
T493 |
punct |
/,sterolin |
R214 |
T496 |
T493 |
punct |
-,sterolin |
R215 |
T497 |
T493 |
nummod |
2,sterolin |